ID A0A3Q7FWU4_SOLLC Unreviewed; 716 AA.
AC A0A3Q7FWU4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=CSC1-like protein HYP1 {ECO:0008006|Google:ProtNLM};
GN Name=101246583 {ECO:0000313|EnsemblPlants:Solyc02g088300.3.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc02g088300.3.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc02g088300.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc02g088300.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc02g088300.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc02g088300.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR RefSeq; XP_004232200.1; XM_004232152.3.
DR RefSeq; XP_010316240.1; XM_010317938.2.
DR AlphaFoldDB; A0A3Q7FWU4; -.
DR STRING; 4081.A0A3Q7FWU4; -.
DR PaxDb; 4081-Solyc02g088300-2-1; -.
DR EnsemblPlants; Solyc02g088300.3.1; Solyc02g088300.3.1; Solyc02g088300.3.
DR GeneID; 101246583; -.
DR Gramene; Solyc02g088300.3.1; Solyc02g088300.3.1; Solyc02g088300.3.
DR KEGG; sly:101246583; -.
DR InParanoid; A0A3Q7FWU4; -.
DR OMA; PKRYYAH; -.
DR OrthoDB; 1753647at2759; -.
DR Proteomes; UP000004994; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IBA:GO_Central.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF109; CSC1-LIKE PROTEIN HYP1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..500
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 548..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 628..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..167
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 188..343
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 356..621
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 716 AA; 81093 MW; 945B15FA40763B9C CRC64;
MILSALLTSV GINLGLCFLF FTLYSILRKQ PGNAEVYAPR LVAEGRSQQI SNFNLERLLP
SAGWVTRAWR PSEAELLANS GLDAVVFMRI FIFSAKVFTF AVIVGIFILL PINYMGNQLS
LDLFDLPNKS LESFTISNVD DGSNRLWIHF SAVYIFTAVV CYLLYIEYDY ISSKRVSYFC
SSKPHPHQFT ILVRSIPASS GRSYSETVES FFSEYYPATY LSHWVVRRAS KLQGLIKNSK
RLYRRLVNLK SANHDRERFG RAGFMGLFGQ RVDLLDHYEK KLEVIEDNVR AEQSSSLGKE
VGAAFVSFRT RFAAASATHM QQGVNPTQWV TEPAPDPEDV YWPFFSASFL KRWISNLVVV
VACVLLTVLF LIPVLIVQGL THLEQLEIWF PFLKGLLRIA FVSQVITGYL PSLVLQLFLY
VVPSIMIMFS SIQGYIAMSQ IEKSACIKVL WFTIWNIFFA NVLSGSALYR VEIFLEPKNI
PAILAVAVPG QATFFIAYVV TSGWTSTSSE LFQLSTLVFN FIKRNICRKY DDEFEVPSVP
YHSEIPRILL FGLLGITYFF LAPLILPFLL VYYCLGYLIY RNQLLNVYAP KYETGGKLWP
IVHDSMIFSL ILMHVIAIGI FGLKKLPLAS SLTVPLPILT LVFNSYCRRR FLPMFKSYSV
ESLLKKDKEE QNDPTIASFH ERLATAYQDP ALLHVGYSGN NASIIAPLLG TAEVDA
//
