ID A0A3Q7FZ11_SOLLC Unreviewed; 1183 AA.
AC A0A3Q7FZ11;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc04g007510.3.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc04g007510.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc04g007510.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc04g007510.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc04g007510.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR RefSeq; XP_004237199.2; XM_004237151.3.
DR AlphaFoldDB; A0A3Q7FZ11; -.
DR STRING; 4081.A0A3Q7FZ11; -.
DR PaxDb; 4081-Solyc04g007510-2-1; -.
DR EnsemblPlants; Solyc04g007510.3.1; Solyc04g007510.3.1; Solyc04g007510.3.
DR GeneID; 101261705; -.
DR Gramene; Solyc04g007510.3.1; Solyc04g007510.3.1; Solyc04g007510.3.
DR KEGG; sly:101261705; -.
DR InParanoid; A0A3Q7FZ11; -.
DR OMA; KMWKMSK; -.
DR OrthoDB; 53793at2759; -.
DR Proteomes; UP000004994; Chromosome 4.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF146; DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH5, MITOCHONDRIAL; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00035; dsrm; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00358; DSRM; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 302..469
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 556..730
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1096..1161
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1076..1097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1183 AA; 133563 MW; B058263985FF9821 CRC64;
MSLYPLQFFT VSSHYRNLRT SSISPPSLTM KDRPLSSCGA VYVPPHQRLR SVITVPSAVS
PQPGSLRPTA IDQKRNPNIF KSYPCLPPQQ QTVRLQHKRS SQFDEVSEEG GDIELTPYQG
AVASDNAEIW KWKLTALLQN NDIQEVLSRE KKDRRDYEQI AALASKMGLY SNLYSKVIVV
SKLPLPNYRF DLDDKRPQRE VILPPGLPRR VDVFLGEYLS RKPRSTDVLS RSSSNGSIAT
DEGLFEQSEA LPQSKASMKK IHWERSMQMQ TEQQTWQESP EGRKMLEFRC SLPAYKEKDA
ILSAISQNQV VIVSGETGCG KTTQIPQFIL ESEIEYIRGD MCSIICTQPR RISVMAVSER
VAAERGELLG ETVGYKVRLE GVKGRDTHLL FCTTGILLRR LLVDRNLKGI THVIVDEIHE
RGMNEDFLLI VLKDLLPRRP ELRLILMSAT LDAELFSSYF NGAPLVHIPG FTYPVHTHFL
ENILEMSGYR LTPDNQIDDY GQERTWKMNK QAPRKRKSQI ASAVEDTLRS ADFQEFSPET
QESLSCWNPD CIGFNFIEYI LCHICENERP GAVLVFMTGW DDISSLKDKL QSHPILGNTS
RVLLLACHGS MASSEQRLIF DKPEDGVRKI VLATNIAETS ITIDDVVFVI DCGKAKETSY
DALNNTPRLL PSWISKVSAR QRRGRAGRVQ PGECYHLYPR CVYDAFADYQ LPEILRTPLQ
SLCLQIKSLK LGSISEFLKR ALQSPELLAV QNAVEYLKII GALDENENLT VLGRYLTMLP
MEPKLGKMLI LGAILNCLDP ILTIVAGLSV RDPFLTPLDK KDLADAAKAH FSRDFSDHLA
LVRAYEGWRD AERDLAGYEY CWKNFLSAQS MKAIDSLRKE FYSLLNDTGL VDSNITMYNS
WSYDEHLLRA IICYGLYPGI CSVLHNEKSF SLKTMEDGQV LLHSNSVNAR DSRIPYPWLV
FNEKIKVNSV FLRDSTAISD SVLLLFGGTI SKGEVDGHLK MLGGYLEFFM NPTIAEMYRS
LRRELDELIH TKLLNPRMDV HSYHELLSAI RLLISEDQCG GRFVFSHQIL LPSKPCAGAP
TPAPTSRIES GPGGDNAKSQ LQTLLNRAGY ATPTYKSLQL NNNQFRATVE FNGMQIMGRP
CNNKKQAEKD AAAEALEWLL EGHRAGPDYI EQMSQFLKKS KKA
//
