ID A0A3Q7G5A0_SOLLC Unreviewed; 863 AA.
AC A0A3Q7G5A0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=101245542 {ECO:0000313|EnsemblPlants:Solyc04g076140.3.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc04g076140.3.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc04g076140.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc04g076140.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc04g076140.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc04g076140.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
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DR RefSeq; XP_010320199.1; XM_010321897.2.
DR AlphaFoldDB; A0A3Q7G5A0; -.
DR STRING; 4081.A0A3Q7G5A0; -.
DR PaxDb; 4081-Solyc04g076140-2-1; -.
DR EnsemblPlants; Solyc04g076140.3.1; Solyc04g076140.3.1; Solyc04g076140.3.
DR GeneID; 101245542; -.
DR Gramene; Solyc04g076140.3.1; Solyc04g076140.3.1; Solyc04g076140.3.
DR KEGG; sly:101245542; -.
DR InParanoid; A0A3Q7G5A0; -.
DR OMA; LMMMQIV; -.
DR OrthoDB; 5395569at2759; -.
DR Proteomes; UP000004994; Chromosome 4.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR025757; MIP1_Leuzipper.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46265; RHO GTPASE-ACTIVATING PROTEIN 7; 1.
DR PANTHER; PTHR46265:SF24; RHO GTPASE-ACTIVATING PROTEIN REN1-LIKE; 1.
DR Pfam; PF14389; Lzipper-MIP1; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994}.
FT DOMAIN 33..140
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 186..385
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..863
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 571..686
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 404..430
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..452
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..846
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 863 AA; 94728 MW; 9CAD358FCB03DDD6 CRC64;
MTTNRSADAS KVEGVNQPPP TPGADDQVRG GNKVYRSGNL FLSSKGIGWT SWKKRWFILT
RTSLVFYRTD PNATPLKGSE VNLTLGGIDL NSSGSVVVKE DKKLLTVLFP DGRDGRAFTL
KAETSEDLLE WKTALEEALA DAPSAALVMG QNGIFNNQAN ADDVSLEQSN DRQPVKSMVI
GRPVLLALED IDGTPSFLEK ALRFVEEHGI RTEGILRQAA DVDDVEQRIR EYEQGKTDFS
TDEDAHVIAD CVKYILRELP SSPVPASCCN ALLEAFKTER SIRVNAMHTA ILETFPEPNR
RLLQRILMMM QTVVSNKTQN RMSTSAVAAC MAPLLLRPLL AGDCELGNDF AMSGDSSVQL
LQAAAAANHA QAIVITLLEE YDKLFGEGSV SPELYSDSDG SGTESGEEFT DDDYSYDEEE
EDDDAEEGSH ADVDDSDHDS CTTTHEVGES EDSNKSSLVS KTSLKTTEVD VVKTTGSSPR
SLPQTSVQND VNKGGESVPP PSRENSRAQG NESAEQVGPG QIEPSTSQKS TNMLNGPLNS
VRRAAIWGRT PAKKNLSMES IEIPFNEEEE IQRLEAIKAD LQTRIQEEAK GNALLQESLE
KRKDALHVRR LALEKDVTRL QEQLQREKEL RILLEAGLEG KLPATYSIDG MMKNELQEIA
QAEADVNNLK QRADDLGLHL SKQREQNSKL LADSGNQPQQ SLNNQGKSKG KHTDTETSKY
EASKQADSSQ SANSSVEAEM SRAASASIRK STSRNEGANT TTSALSKLTN RLNFLKERRT
QIASELQYLD KNQSDQAVKN NGKVQASRSQ TAEKNRLNDR QSLQHPDQGT KKEVHPNLDK
VKSDSLPNTE KGQAVVPPWT NSR
//
