ID A0A3Q7GRY0_SOLLC Unreviewed; 408 AA.
AC A0A3Q7GRY0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=glutathione transferase {ECO:0000256|ARBA:ARBA00012452};
DE EC=2.5.1.18 {ECO:0000256|ARBA:ARBA00012452};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc06g009040.3.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc06g009040.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc06g009040.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc06g009040.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc06g009040.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glutathione + RX = a halide anion + an S-substituted
CC glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925,
CC ChEBI:CHEBI:90779; EC=2.5.1.18;
CC Evidence={ECO:0000256|ARBA:ARBA00000710};
CC -!- SIMILARITY: Belongs to the GST superfamily. Phi family.
CC {ECO:0000256|ARBA:ARBA00010128}.
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DR AlphaFoldDB; A0A3Q7GRY0; -.
DR SMR; A0A3Q7GRY0; -.
DR STRING; 4081.A0A3Q7GRY0; -.
DR PaxDb; 4081-Solyc06g009040-2-1; -.
DR EnsemblPlants; Solyc06g009040.3.1; Solyc06g009040.3.1; Solyc06g009040.3.
DR Gramene; Solyc06g009040.3.1; Solyc06g009040.3.1; Solyc06g009040.3.
DR InParanoid; A0A3Q7GRY0; -.
DR OMA; FEGSAIM; -.
DR Proteomes; UP000004994; Chromosome 6.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0043295; F:glutathione binding; IBA:GO_Central.
DR GO; GO:0004364; F:glutathione transferase activity; IBA:GO_Central.
DR GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR GO; GO:0009407; P:toxin catabolic process; IEA:UniProt.
DR CDD; cd03187; GST_C_Phi; 2.
DR CDD; cd03053; GST_N_Phi; 2.
DR Gene3D; 1.20.1050.10; -; 2.
DR Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR034347; GST_Phi_C.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43900; GLUTATHIONE S-TRANSFERASE RHO; 1.
DR PANTHER; PTHR43900:SF27; GLUTATHIONE S-TRANSFERASE-LIKE; 1.
DR Pfam; PF00043; GST_C; 2.
DR Pfam; PF02798; GST_N; 2.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG01154; Main.5:_Phi-like; 2.
DR SFLD; SFLDG00358; Main_(cytGST); 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 2.
DR SUPFAM; SSF52833; Thioredoxin-like; 2.
DR PROSITE; PS50405; GST_CTER; 2.
DR PROSITE; PS50404; GST_NTER; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..82
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 89..224
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT DOMAIN 197..278
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 285..408
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
SQ SEQUENCE 408 AA; 45700 MW; EA139C42AC7598BB CRC64;
MAIKVHGPMM SPAVMRVVAT LKEKDLDFEL VPVNMQAGDH KKEPFISLNP FGQVPAFEDG
DLKLFESRAI TQYIAHTYAD KGNQLLPNDP KKMAVMSVWM EVEAQKFDPI GSKLGFEIVI
KPMLGMVTDD AVVAENEEKL GKLLDVYESR LKESKYLGGE SFTLADLHHA PSLHYLSGSK
VKSLFDARPH LGLRQLSCQN IHGPMLSPAV VRVVAMLKEK NLDFELVHVD LQNGDQKKEP
FISLNPFGQV PAFEDGDLKL FESRAITQYI AHTYADKGNQ LLPNDPKKMA IMYVWIEVEA
QRFEPVVSKL CYEIVIKPLL DMVTDDAIVA ENEEKLSKLL DVYESRLKDS KYLGGDSFTL
ADLNHAPALH YLMGTKVKSL FNARPHVGAW VANILARPAW AKSLELTK
//
