ID   A0A3Q7GXD0_SOLLC        Unreviewed;       252 AA.
AC   A0A3Q7GXD0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Bidirectional sugar transporter SWEET {ECO:0000256|RuleBase:RU910715};
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc06g060580.2.1};
RN   [1] {ECO:0000313|EnsemblPlants:Solyc06g060580.2.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc06g060580.2.1};
RX   PubMed=22660326; DOI=10.1038/nature11119;
RG   Tomato Genome Consortium;
RT   "The tomato genome sequence provides insights into fleshy fruit
RT   evolution.";
RL   Nature 485:635-641(2012).
RN   [2] {ECO:0000313|EnsemblPlants:Solyc06g060580.2.1}
RP   IDENTIFICATION.
RC   STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc06g060580.2.1};
RG   EnsemblPlants;
RL   Submitted (JAN-2019) to UniProtKB.
CC   -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC       the membrane. {ECO:0000256|RuleBase:RU910715}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU910715};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU910715}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC       {ECO:0000256|ARBA:ARBA00007809, ECO:0000256|RuleBase:RU910715}.
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DR   RefSeq; XP_004242288.1; XM_004242240.2.
DR   AlphaFoldDB; A0A3Q7GXD0; -.
DR   STRING; 4081.A0A3Q7GXD0; -.
DR   PaxDb; 4081-Solyc06g060580-1-1; -.
DR   EnsemblPlants; Solyc06g060580.2.1; Solyc06g060580.2.1; Solyc06g060580.2.
DR   GeneID; 101248588; -.
DR   Gramene; Solyc06g060580.2.1; Solyc06g060580.2.1; Solyc06g060580.2.
DR   KEGG; sly:101248588; -.
DR   InParanoid; A0A3Q7GXD0; -.
DR   OMA; IPYVMAF; -.
DR   OrthoDB; 66728at2759; -.
DR   Proteomes; UP000004994; Chromosome 6.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051119; F:sugar transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR   Gene3D; 1.20.1280.290; -; 2.
DR   InterPro; IPR047664; SWEET.
DR   InterPro; IPR004316; SWEET_rpt.
DR   PANTHER; PTHR10791:SF192; BIDIRECTIONAL SUGAR TRANSPORTER SWEET; 1.
DR   PANTHER; PTHR10791; RAG1-ACTIVATING PROTEIN 1; 1.
DR   Pfam; PF03083; MtN3_slv; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910715};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|RuleBase:RU910715};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU910715};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU910715};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU910715}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910715"
FT   TRANSMEM        46..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910715"
FT   TRANSMEM        71..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910715"
FT   TRANSMEM        103..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910715"
FT   TRANSMEM        136..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910715"
FT   TRANSMEM        164..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910715"
FT   TRANSMEM        192..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU910715"
SQ   SEQUENCE   252 AA;  28147 MW;  43A31BC634ABD734 CRC64;
     MRGLVHTIQF VFGILGNVAT LFLFLVPTHT FKRIIKNKST EQFSGIPYVM AFLNCLISAW
     YGLPFVTSNN ILVATINGTG AAIELIYVLI FLLYAPNKQK RRIFAIFVLV VVAFAAAAVI
     SVLFFHGKNR KLFCGIASTV FSIVMYAAPL SIIRLVITTK SVEYMPFLLS FAAILSCTSW
     FIYAILGMDP YIGISTGVGL TLGIVQLVLY FSYCDKRILN KKTFAVEESQ KNMDNDVKPY
     DESIHECPYV KV
//