ID   A0A3Q7HT55_SOLLC        Unreviewed;       520 AA.
AC   A0A3Q7HT55;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Carotenoid cleavage dioxygenase 4 {ECO:0008006|Google:ProtNLM};
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc08g075490.3.1};
RN   [1] {ECO:0000313|EnsemblPlants:Solyc08g075490.3.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc08g075490.3.1};
RX   PubMed=22660326; DOI=10.1038/nature11119;
RG   Tomato Genome Consortium;
RT   "The tomato genome sequence provides insights into fleshy fruit
RT   evolution.";
RL   Nature 485:635-641(2012).
RN   [2] {ECO:0000313|EnsemblPlants:Solyc08g075490.3.1}
RP   IDENTIFICATION.
RC   STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc08g075490.3.1};
RG   EnsemblPlants;
RL   Submitted (JAN-2019) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC         Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC       Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC   -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC       {ECO:0000256|ARBA:ARBA00006787}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q7HT55; -.
DR   STRING; 4081.A0A3Q7HT55; -.
DR   PaxDb; 4081-Solyc08g075490-2-1; -.
DR   EnsemblPlants; Solyc08g075490.3.1; Solyc08g075490.3.1; Solyc08g075490.3.
DR   Gramene; Solyc08g075490.3.1; Solyc08g075490.3.1; Solyc08g075490.3.
DR   InParanoid; A0A3Q7HT55; -.
DR   OMA; KTEECWY; -.
DR   Proteomes; UP000004994; Chromosome 8.
DR   GO; GO:0009570; C:chloroplast stroma; IBA:GO_Central.
DR   GO; GO:0010436; F:carotenoid dioxygenase activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016121; P:carotene catabolic process; IBA:GO_Central.
DR   InterPro; IPR004294; Carotenoid_Oase.
DR   PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR   PANTHER; PTHR10543:SF46; CAROTENOID CLEAVAGE DIOXYGENASE 4, CHLOROPLASTIC-RELATED; 1.
DR   Pfam; PF03055; RPE65; 1.
PE   3: Inferred from homology;
KW   Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW   Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|PIRSR:PIRSR604294-1};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00022964};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004994}.
FT   BINDING         216
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT   BINDING         265
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT   BINDING         330
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT   BINDING         508
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ   SEQUENCE   520 AA;  57057 MW;  A05373A5DD30D6C7 CRC64;
     MDALKPIEPS FPSFIFNAFD DFVNTFIDPP RKSSVDPRYV LSNNFAPVDE LPPTECEVVE
     GSLPPCLDGA YIRNGPNPQY LPRGPYHLFD GDGMLHSIKI SQGKATLCSR FVKTYKYNIE
     NEAGSPIIPN VFSGFNGLTA SAARGALTAA RAIAGQFNPA NGIGLANTSL ALFGGKLFAL
     GESDLPYEVK IAPNGDIFTL GRHDFNGKLS MSMTAHPKID HETNEAFAFR YGPIPPFITY
     FRVNPDGTKT QDVPIFSMTR PSFLHDFAIT KKYAIFSDIQ IGMNPIDLLT GGSPVGTDSG
     KIPRIGVIPR YAKDESEMRW FDVSGFNIVH AINAWDEDGG DTIVLIAPNI LSVEHTLERM
     DMIHASVEKV KINLKTGMVS RHPISTRNLD FGVINPAYVG KKNKYVYAAI GGPMPKVIGI
     AKLDVSVAEI DRRDCIVACR IFGKDCYGGE PFFVPKNPSI DEDDGYVVSY VHNEKTGESN
     FLVMDATSPN LDIVANVKLP RRVPYGFHGL FVSENDLMKL
//