ID A0A3Q7I2I7_SOLLC Unreviewed; 677 AA.
AC A0A3Q7I2I7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=101264442 {ECO:0000313|EnsemblPlants:Solyc07g017860.3.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc07g017860.3.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc07g017860.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc07g017860.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc07g017860.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc07g017860.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- PATHWAY: Phytoalexin biosynthesis; 3,4',5-trihydroxystilbene
CC biosynthesis; 3,4',5-trihydroxystilbene from trans-4-coumarate: step
CC 1/2. {ECO:0000256|ARBA:ARBA00004930}.
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DR RefSeq; XP_004242910.1; XM_004242862.3.
DR AlphaFoldDB; A0A3Q7I2I7; -.
DR STRING; 4081.A0A3Q7I2I7; -.
DR PaxDb; 4081-Solyc07g017860-2-1; -.
DR EnsemblPlants; Solyc07g017860.3.1; Solyc07g017860.3.1; Solyc07g017860.3.
DR GeneID; 101264442; -.
DR Gramene; Solyc07g017860.3.1; Solyc07g017860.3.1; Solyc07g017860.3.
DR KEGG; sly:101264442; -.
DR InParanoid; A0A3Q7I2I7; -.
DR OMA; IRALMRC; -.
DR OrthoDB; 144557at2759; -.
DR UniPathway; UPA00372; UER00547.
DR Proteomes; UP000004994; Chromosome 7.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IBA:GO_Central.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006085; P:acetyl-CoA biosynthetic process; IBA:GO_Central.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR GO; GO:0009698; P:phenylpropanoid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR HAMAP; MF_01123; Ac_CoA_synth; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF247; ACETYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phenylpropanoid metabolism {ECO:0000256|ARBA:ARBA00023051};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994}.
FT DOMAIN 44..104
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 112..499
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 561..639
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 677 AA; 75387 MW; 25F8DA01BF8B8C67 CRC64;
MKEINCSNNN NIVLGEGLAS EEVNFVIPSH EFSKQAHVSS LQKYEEMYGK SMEDPAGFWS
EIASEFYWKQ KWGQPVYTDN LDIRNGKINI QWFKDGKTNI CYNCLDRNID AGNGDKFAIL
WEGNDLGRDA TLTYTQLLAR VCQLANYLKS IGVGKGDAVI IYLPMLMELP IAMLACARIG
AVHSVVFAGF SAESLAQRIV DCKPKVVITC SAVKRGAKTI FLKDIVDDAL TQSAQNSVKI
DVCLTFENES ALQKQMTKWV EGRDIWWQDV VPKYPVTCDV EWVDAEDPLF LLYTSGSTGK
PKGVLHTTGG YMVYTATTFK YAFDYKPKDI YWCTADCGWI TGHSYVTYGP LLNGATNVVF
EGAPNYPDAG RCWDIVDKYK VSIFYTAPTL VRSLMREGDE HVTRYSRKSL RVLGSVGEPI
NPSAWRWFFN VVGDGKCPIS DTWWQTETGG FMITPMPGAW PQKPGSATLP FFGVQPVIVD
EKGVELKGEC SGYLCVKNSW PSAFRTLYGD HERYETTYFS AFPGYYFTGD GCNRDKDGYY
WLTGRVDDVI NVSGHRIGTA EVESALVSHP QCVEAAVVGV EHDVKGQGIY VFVTLAEGVS
YSEELRRSLI KVVRDKIGGF AAPDKIHWAP GLPKTRSGKI MRRILRKIAS NSLDELGDTS
TLADPTVVDQ LIALAHS
//
