ID A0A3Q7IYL2_SOLLC Unreviewed; 497 AA.
AC A0A3Q7IYL2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914};
DE AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc11g065820.2.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc11g065820.2.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc11g065820.2.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc11g065820.2.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc11g065820.2.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199,
CC ECO:0000256|RuleBase:RU004914}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU004914}.
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DR AlphaFoldDB; A0A3Q7IYL2; -.
DR PaxDb; 4081-Solyc11g065820-1-1; -.
DR EnsemblPlants; Solyc11g065820.2.1; Solyc11g065820.2.1; Solyc11g065820.2.
DR Gramene; Solyc11g065820.2.1; Solyc11g065820.2.1; Solyc11g065820.2.
DR InParanoid; A0A3Q7IYL2; -.
DR OMA; WDELGRE; -.
DR Proteomes; UP000004994; Chromosome 11.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13136; MATE_DinF_like; 1.
DR InterPro; IPR044644; DinF-like.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR42893:SF4; PROTEIN DETOXIFICATION 42; 1.
DR PANTHER; PTHR42893; PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU004914};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW Transmembrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane helix {ECO:0000256|RuleBase:RU004914}.
FT TRANSMEM 154..181
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 226..247
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 253..271
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 292..314
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 375..398
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 404..428
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 440..459
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 465..485
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT REGION 99..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 53582 MW; 3B62CF3B7A0A1284 CRC64;
MSRSVFKLDE LGREIARIAL PAALALTADP IASLVDTAFI GQIGPVELAA VGISIAVFNQ
ASRIAIFPLV SVTTSFVAEE DTITKVSSMP RDNEIQDIQS QDVEGLDTES QSNSENKELI
PQNRSVYKSE TTATSFEVVK PKPEKRHIPS ASSALIIGAI LGFIQAAFLI SGAKPILSFM
GVKHGSPMLK PAQEYLKLRS LGAPAVLLSL AMQGVFRGFK DTKTPLFATV AGDLTNIILD
PIFIFAFHMG VRGAAIAHVI SQYLISAILF WRLMEKVDLL PPSLKYMQFS RFLTNGFLLL
MRVIAVTFCV TLAASLAARL GPTEMAAFQV CLQVWLTVSL LADGLAVAGQ AILASAFAQN
DYNRATATAS RVLQLGLVLG LVLAVILGVG LHFGARLFTE DVNVIHLIGI GMPFVAATQP
INALAFVFDG VNFGASDFAY SAYSMVTVAL FSILFLFILS SSYKFVGIWV ALTIYMSLRA
LAGFWRIGTR TGPWKFL
//
