ID   A0A3Q7J037_SOLLC        Unreviewed;       591 AA.
AC   A0A3Q7J037;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=ENTH domain-containing protein {ECO:0000259|PROSITE:PS50942};
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc11g070110.2.1};
RN   [1] {ECO:0000313|EnsemblPlants:Solyc11g070110.2.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc11g070110.2.1};
RX   PubMed=22660326; DOI=10.1038/nature11119;
RG   Tomato Genome Consortium;
RT   "The tomato genome sequence provides insights into fleshy fruit
RT   evolution.";
RL   Nature 485:635-641(2012).
RN   [2] {ECO:0000313|EnsemblPlants:Solyc11g070110.2.1}
RP   IDENTIFICATION.
RC   STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc11g070110.2.1};
RG   EnsemblPlants;
RL   Submitted (JAN-2019) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC       {ECO:0000256|ARBA:ARBA00004132}. Vesicle
CC       {ECO:0000256|ARBA:ARBA00004373}.
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DR   AlphaFoldDB; A0A3Q7J037; -.
DR   STRING; 4081.A0A3Q7J037; -.
DR   PaxDb; 4081-Solyc11g070110-1-1; -.
DR   EnsemblPlants; Solyc11g070110.2.1; Solyc11g070110.2.1; Solyc11g070110.2.
DR   Gramene; Solyc11g070110.2.1; Solyc11g070110.2.1; Solyc11g070110.2.
DR   InParanoid; A0A3Q7J037; -.
DR   OMA; ANFMDEP; -.
DR   Proteomes; UP000004994; Chromosome 11.
DR   GO; GO:0030125; C:clathrin vesicle coat; IBA:GO_Central.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0030276; F:clathrin binding; IBA:GO_Central.
DR   GO; GO:0005543; F:phospholipid binding; IBA:GO_Central.
DR   GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR   CDD; cd03571; ENTH; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   PANTHER; PTHR12276:SF45; ENTHOPROTIN-RELATED; 1.
DR   PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   PROSITE; PS50942; ENTH; 1.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004994}.
FT   DOMAIN          20..166
FT                   /note="ENTH"
FT                   /evidence="ECO:0000259|PROSITE:PS50942"
FT   REGION          185..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          467..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        185..215
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        216..240
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        241..260
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..486
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   591 AA;  64142 MW;  E71F9F8A079C65F0 CRC64;
     MDFMKVFDQT VREIKREVNL KVLQVPEIEQ KVLDATDDEP WGPHGTALAD IAQATKKLYD
     LNDKVANSYE FCSECQMVMN VLWSRLPETG KNWRYVYKSL SVIEYLVAHG SERAVDEIVE
     HTYQISSLAS FEYVEPNGKD MGINVRKKAE NIVALLNNKE KIQEVREKAS ANRDKYFGLS
     SSGVTFKSSS SSFSSSGNFQ SSDRYGGFGN KNDGNSFKDS YKEKDRYGED KVDRSTFKSK
     KGSSHYGSNV QATASASGSK TAKRVGKPDK ACSSPSQSAA ASSSKYEEDF DDFDPRGTSS
     TKPSTGNSGQ VDLFGQNLMG DLLDAPTSVP ADNSSVTSHP SEVDLFADAN FVSVKPESKV
     GVTFCLLFRL PCNFYFLFVS YKLTICSFLQ ISVDLFASQP SSSPVASSTM DFFAAPEPVA
     RPDVISPKSV QINTTMVDPF ATVPLNNFDS SDPFGAFVSP ADPISVPNAS ATSGGNQQTP
     TKLDKSPLET KPSPKKDNFQ VSSGIWADSL SRGLIDLNIA APTKVNLADV GIMGGLTDGS
     DGKEKGPTTF YMGRAMGQGT KLGQSGFTST ATGADDFFSS HQNYQFGNFQ K
//