ID   A0A3Q7J3P4_SOLLC        Unreviewed;       487 AA.
AC   A0A3Q7J3P4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 20 {ECO:0000256|RuleBase:RU364152};
DE   AltName: Full=Mediator complex subunit 20 {ECO:0000256|RuleBase:RU364152};
GN   Name=MED20 {ECO:0000256|RuleBase:RU364152};
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc12g009090.2.1};
RN   [1] {ECO:0000313|EnsemblPlants:Solyc12g009090.2.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc12g009090.2.1};
RX   PubMed=22660326; DOI=10.1038/nature11119;
RG   Tomato Genome Consortium;
RT   "The tomato genome sequence provides insights into fleshy fruit
RT   evolution.";
RL   Nature 485:635-641(2012).
RN   [2] {ECO:0000313|EnsemblPlants:Solyc12g009090.2.1}
RP   IDENTIFICATION.
RC   STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc12g009090.2.1};
RG   EnsemblPlants;
RL   Submitted (JAN-2019) to UniProtKB.
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC       the regulated transcription of nearly all RNA polymerase II-dependent
CC       genes. Mediator functions as a bridge to convey information from gene-
CC       specific regulatory proteins to the basal RNA polymerase II
CC       transcription machinery. Mediator is recruited to promoters by direct
CC       interactions with regulatory proteins and serves as a scaffold for the
CC       assembly of a functional preinitiation complex with RNA polymerase II
CC       and the general transcription factors. {ECO:0000256|RuleBase:RU364152}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364152}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU364152}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 20 family.
CC       {ECO:0000256|ARBA:ARBA00010743, ECO:0000256|RuleBase:RU364152}.
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DR   AlphaFoldDB; A0A3Q7J3P4; -.
DR   STRING; 4081.A0A3Q7J3P4; -.
DR   PaxDb; 4081-Solyc12g009090-1-1; -.
DR   EnsemblPlants; Solyc12g009090.2.1; Solyc12g009090.2.1; Solyc12g009090.2.
DR   Gramene; Solyc12g009090.2.1; Solyc12g009090.2.1; Solyc12g009090.2.
DR   InParanoid; A0A3Q7J3P4; -.
DR   Proteomes; UP000004994; Chromosome 12.
DR   GO; GO:0016592; C:mediator complex; IBA:GO_Central.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR013921; Mediator_Med20.
DR   PANTHER; PTHR12465:SF0; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20; 1.
DR   PANTHER; PTHR12465; UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49; 1.
DR   Pfam; PF08612; Med20; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364152};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364152};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW   Transcription {ECO:0000256|RuleBase:RU364152};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364152}.
SQ   SEQUENCE   487 AA;  55656 MW;  29A6BCAF2CF9A565 CRC64;
     MEEGGLSQSG EEPKSWDELY NVNLMPSEIF LKFRKEIEGY RVGVNLEFYN APYNEYLAKL
     VLKPLAPERR WKFIYEPLNH EVRLLSKKIP VTKFLNLQVG VGHSFKLQAT GWKWKLTSCF
     GGDGISSIRN KTSLGLCPGV DFRFGWKADY VFPEVTGQVT LSSFALHFKE THLLNDILLA
     LGTGEPLFNM NSGRLQASLD RDMLLIDIDI SQQIIDLLEN VEEIIEGENH LSSFHREELK
     GFSGVSSSGE LSGKRKGNLG FNFLRRTFRV LHWQPNAGTT VNSQILTEVS QCVESINGVK
     EGRWKDTLSF YKPMLRVEQA NSLEFPRDFL GISLQEQPNK YYMVIRGQRL IIEAESSIQT
     IMEKLQSYKT RVALNFEGFQ YQLGDFQLRV GKVVTIHSEN LRGIVMEMEY LPISSWETSH
     QIMGEFFDIW QEALGKRSLP GHFVHVEPNF SEYGLSDQYT SQHTAVQYAS IMAQMIATAQ
     SSQPMRN
//