ID A0A3Q7JY12_SOLLC Unreviewed; 824 AA.
AC A0A3Q7JY12;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc12g089010.2.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc12g089010.2.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc12g089010.2.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc12g089010.2.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc12g089010.2.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR AlphaFoldDB; A0A3Q7JY12; -.
DR STRING; 4081.A0A3Q7JY12; -.
DR PaxDb; 4081-Solyc12g089010-1-1; -.
DR EnsemblPlants; Solyc12g089010.2.1; Solyc12g089010.2.1; Solyc12g089010.2.
DR Gramene; Solyc12g089010.2.1; Solyc12g089010.2.1; Solyc12g089010.2.
DR InParanoid; A0A3Q7JY12; -.
DR OMA; VVYHEAI; -.
DR Proteomes; UP000004994; Chromosome 12.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.10.10.2130; DEAH helicase family, winged-helix domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR042035; DEAH_win-hel_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF233; RNA HELICASE; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994}.
FT DOMAIN 227..390
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 412..592
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 824 AA; 93403 MW; F09B0BDED0889800 CRC64;
MNRIKELEFK HQWRRRIEEA NPWNREGERE PVAKNIHMLL LLLLHGTLWL LLQFQLGVGK
NWEDHQLLRS GAVRGNKVET GFDDDEEERK VILHVCDVKL PPFLDGRVFT DQAELILPIK
DAMSDMAVIS RKGSALVREI HEKQKRDKSR QRFWELAGSK LGDILGVEKS VDETDADTVV
VGEDGEVDFK GKARFSQHLS VGDFTKSKTI SQQRQNLPIF SVRDELLQVV RENQVVVIIG
ETGSGKTTQL TQYLYEYGYT VNGIIGCTQP RRVAAMSVAK RVSEEMESEL GDKVGYAIRF
EDATGPSTVI KYMTDGVLLR ETLKDPDLEK YSMILMDEAH ERSLDTDVLF GILKKVVARR
RDFKLIVTSA TLNGEKFSNF FGGVPIFNIP GRTFRVQICH SKTPCEDYVE AAVKQAMTIH
IAGAPGDILI FLTGQDEIEA TCYALSERME QLISSTEQPV PKLLILPIYS QLPADLQAKI
FHKAEDGARK CIVATNIAET SLTIDGIFYV IDTGYGKMKV YNPCMGMDAL QVFPISRASA
DQRAGRAGRT GPGTCYRLYT ENAYENEMLQ SPVPEIQRTN LGNVVLLLKS LKIQNLLDFD
FMDPPPQDNI LNSMYQLWLL GALNDVGDLT DLGRKMVKFP LDPVLTIVSM LSVPSVFFRP
KDREAESDAA REKFFVPESD HLTLLNVYQQ WKANEYRGDW CNDHFLQVKG LYKAREIRFQ
LLDILKTLKI PLTYCGPDWD VVRKTICSTY FHNAAMLKGI GEYVNCRNRM PCNLHPTSAL
YGLGYTPDYV VYHEAILTTK EYMQCVTAVE PHWLAELGPM FFSV
//
