ID A0A3Q7QVI7_VULVU Unreviewed; 1410 AA.
AC A0A3Q7QVI7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Protein Shroom4 isoform X2 {ECO:0000313|RefSeq:XP_025838164.1};
GN Name=SHROOM4 {ECO:0000313|RefSeq:XP_025838164.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025838164.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025838164.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025838164.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025838164.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the shroom family.
CC {ECO:0000256|ARBA:ARBA00006469}.
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DR RefSeq; XP_025838164.1; XM_025982379.1.
DR Ensembl; ENSVVUT00000032757; ENSVVUP00000024771; ENSVVUG00000018168.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR Gene3D; 6.10.250.3120; -; 1.
DR InterPro; IPR014799; ASD2_dom.
DR InterPro; IPR027685; Shroom_fam.
DR PANTHER; PTHR15012; APICAL PROTEIN/SHROOM-RELATED; 1.
DR PANTHER; PTHR15012:SF35; PROTEIN SHROOM4; 1.
DR Pfam; PF08687; ASD2; 1.
DR PROSITE; PS51307; ASD2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT DOMAIN 1113..1404
FT /note="ASD2"
FT /evidence="ECO:0000259|PROSITE:PS51307"
FT REGION 94..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 664..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 824..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1321..1348
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 117..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..322
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..485
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..609
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..693
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 969..983
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1001..1019
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1410 AA; 156284 MW; A39EA4B38A19D93B CRC64;
MHFPSEAFSL SWHSGCNTGD VCVQWCPLSR HCSTEKSSSI GSMESLEQPG QATYEGHLLP
IDQNMYPNQR DSAYSSFSAS SNASDCAFSL RPEEPGSADC IMQGSGPAKA PNGRPSVAET
SGGSQHPSGS HLTLNSQMSS CPEEDHHSEP AKAARGPPQP PVRRDSLQAS RAQLLNGEQR
RASEPVDSLQ QEKVSLDTVL SPRNPNRFCC LSGQDQVTNE GHQNCEFSQA PESSQQDSEH
LIMEASAKAA GFPKACDKAS RIDYSPLNKA SAELAKASFG SPPHLTGPTG HRHSAPEQLL
ASHLQHGHLD TRGSKGTELP AGHDGHEWTL SPLHSSHTGK KSPCPPTGGT QDQHSKERKA
RQVDDRPLCS GHQSPSSSPL GEADGHPPEK GFQDPNRASR AGSESASQQP SASGSLIQQT
RDCSSTTKVV GSTEATEEGD SEPKECGWVG GRRHGGPRGR SIQNRRKSER FATNLRNEIQ
RRKAQLQKSK NSLSQLCDTQ EPVEETEEPL ESPPPPTSNS SLLSSYKKPP SPRDKLFTKS
MILRARSSEC LSQAPESHES RTGLEGQISP GQRPGQPSLG LNTWWKVSDS SPSDSEKTNA
HRGVRGGHWR WSPEHNLQPH VALAMESPSN LGDSKELKAS TAPAGEEAIL LPFADRRKLF
EEGSKSLSTS HLPGLTTHSS KTFTQRPKPV DPNFQPLSSS YRELRHHPMD QSYHATDQSY
HSVSLLQSET PPYSECFASK GLEQSMCCKP LHCGDFDYHR TCSYSCSVQG AIVHDPCMYC
SGEICPALRK RNMMPNCYNC WCHHHQCFRC SACYHNPQHN SPEDGSLAPG NTWKPRKPTM
QEFPGDKWKP ITGNRKTSQS GREMAHPKAS LSWATPFHLE NPPLDLSSYR AISSLDLLGD
FKHSSKKTDE TSLYEEGRSM ASVPYPLRSR AFSESHINLE PQSSRAWGQH RRELFTKVDE
TQPDPLGARK KAFPPPRPPP PNWEKYRLFR AVQQQQQQQQ QEEEAEEEED EEQEERGEKG
GEEEELPPQY FSSETTGMRA LHPEGVLEQP QPLGFGHLEA PRQSLPSFPA EQESFDLHPG
NFLPPIRSHL GSPPEKAQHP GYYGTGRLWR TSEKETTDSP KPEALIAEES KPKAAWSQSY
FFPEEQFSCM GWGSEKQHLS PAGFSEPKTT GQEFQHFKPP LGAPGIPTSY SAYYNISVAK
AELLNKLKDQ PEMAEIGLGE EEVDPELAQK KIQLIESIGR KLSVLREAQR GLLEDISANS
ALGEEVEANL KAICKSNEFE KYRLFIGDLD KVVNLLLSLS GRLARVENAL NSIDAEANQE
KLVLIEKKQQ LKGQLEDAKE LKEHVDRREK LVFGMVSRYL PQDQLQDYQH FVKMKSALII
EQRELEEKIK LGEEQLKCLR ESLLLGPSNF
//
