ID A0A3Q7QYJ0_VULVU Unreviewed; 996 AA.
AC A0A3Q7QYJ0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=RNA-binding protein 10 isoform X5 {ECO:0000313|RefSeq:XP_025838243.1};
GN Name=RBM10 {ECO:0000313|RefSeq:XP_025838243.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025838243.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025838243.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025838243.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025838243.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_025838243.1; XM_025982458.1.
DR AlphaFoldDB; A0A3Q7QYJ0; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd16167; OCRE_RBM10; 1.
DR CDD; cd12753; RRM1_RBM10; 1.
DR CDD; cd12754; RRM2_RBM10; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR041591; OCRE.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR035618; RBM10_OCRE.
DR InterPro; IPR034992; RBM10_RRM2.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR13948:SF4; RNA-BINDING PROTEIN 10; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF17780; OCRE; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF00641; zf-RanBP; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00360; RRM; 2.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 2.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 194..274
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 277..307
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 365..449
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 825..855
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 924..970
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 1..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 687..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 778..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 884..927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..126
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..191
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..718
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 803..819
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 884..902
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 996 AA; 110277 MW; D79BCDE2B33D0BE7 CRC64;
MSGSPPLTAR AEKVSVVAGR GGGESLQEAS PRLADHGGSS GGSWEVKRSQ RLRRGPSSPR
RPYQDMEYER RGGRGDRTGR YGATDRSQDD GGENRSRDHD YRDMDYRSYP REYSSQEGKH
DYDDSSEEQS AEDSYEASPG SETQRRRRRR HRHSPTGPPG FPRDGDYRDQ DYRTEQGEEE
EEDEEEEEEE KASNIVMLRM LPQAATEDDI RGQLQSHGVQ AREVRLMRNK SSGQSRGFAF
VEFSHLQDAT RWMEANQHSL NILGQKVSMH YSDPKPKINE DWLCNKCGVQ NFKRREKCFK
CGVPKSEAEQ KLPLGARLDQ QTLPLGGREL SQGLLPLPQP YQAQGVLASQ ALSQGSEPSS
ENANDTIILR NLNPHSTMDS ILGALAPYAV LSSSNVRVIK DKQTQLNRGF AFIQLSTIVE
AAQLLQILQA LHPPLTIDGK TINVEFAKGS KRDMASNEGS RINAASVAST AIAAAQWAIS
QASQGGEGAW ATPEEPPVDY SYYQQDEGYG GSQGTESSLY AHGYLKGTKG PGITGTKGDP
SGAGSEASLE PGADPVSLQA FSRAQPGAAP GIYQQSAAEA SGSQGAAANS QSYTIMSPAV
LKSELQSPTH PSSALPPATS PTAQESYSQY PVPDVSTYQY DETSGYYYDP QTGLYYDPNS
QYYYNAQSQQ YLYWDGERRT YVPALEQSAD GHKETGAPSK EGKEKKEKHK TKTAQQIAKD
MERWARSLNK QKENFKNSFQ PISSLRDDER RESATADAGY AILEKKGALA ERQHTSMDLP
KLASDDRPSP PRGLVAAYSG ESDSEEEQER GGPEREEKLT DWQKLACLLC RRQFPSKEAL
IRHQQLSGLH KQNLEIHRRA HLSENELEAL EKNDMEQMKY RDRAAERREK YGIPEPPEPK
RRKYGGMSAA SVDFEQPTRD GLGSDNIGSR MLQAMGWKEG SGLGRKKQGI VTPIEAQTRV
RGSGLGARGS SYGVTSTESY KETLHKTMVT RFNEAQ
//
