ID A0A3Q7R5M6_VULVU Unreviewed; 694 AA.
AC A0A3Q7R5M6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Forkhead box protein P1 isoform X8 {ECO:0000313|RefSeq:XP_025840652.1};
GN Name=FOXP1 {ECO:0000313|RefSeq:XP_025840652.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025840652.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025840652.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025840652.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025840652.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_025840652.1; XM_025984867.1.
DR AlphaFoldDB; A0A3Q7R5M6; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR032354; FOXP-CC.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45796; FORKHEAD BOX P, ISOFORM C; 1.
DR PANTHER; PTHR45796:SF3; FORKHEAD BOX PROTEIN P1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR Pfam; PF16159; FOXP-CC; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT DOMAIN 466..552
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 466..552
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 628..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..642
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 694 AA; 77392 MW; CC95F0C3F08ACE33 CRC64;
MMQESGTETK SNGSAIQNGS SGGNHLLPCA SLREGRSNGE TPAADAGAAE LAHVQQQQQQ
QALQVARQLL LQQQQQQQVS GLKSPKRNDK QPALQVPVSV AMMTPQVITP QQMQQILQQQ
VLSPQQLQVL LQQQQALMLQ QQQLQEFYKK QQEQLQLQLL QQQHAGKQPK EQQQVATQQL
AFQQQLLQMQ QLQQQHLLSL QRQGLLTIQP GQPALPLQPL AQGMIPTELQ QLWKEVTSAH
SAEESTGSNH SSLDLTTTCV SSSAPSKTSL IMNPHASTNG QLSVHTPKRE SLSHEEHPHS
HPLYGHGVCK WPGCEAVCED FQSFLKHLNS EHALDDRSTA QCRVQMQVVQ QLELQLAKDK
ERLQAMMTHL HVKSTEPKAA PQPLNLVSSV TLSKSASEAS PQSLPHTPTT PTAPITPVTQ
GPSVITTTSM HTVGPIRRRY SDKYNVPISS ADIAQNQEFY KNAEVRPPFT YASLIRQAIL
ESPEKQLTLN EIYNWFTRMF AYFRRNAATW KGAIRTNLSL HKCFIRVEDE FGSFWTVDDE
EFKRGRHIQR GRPRKYCPGE NFDELVTHNP SLIKNMQSSH AYCTPLNAAL QASMAENSIP
LYTTASMGNP TLGNLASAIR EELNGAMEHT NSNESDSSPG RSPMQAVHPV HVKEEPLDPE
EAEGPLSLVT TANHSPDFDH DRDYEDEPVN EDME
//
