ID   A0A3Q7R5S4_VULVU        Unreviewed;       763 AA.
AC   A0A3Q7R5S4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Heterogeneous nuclear ribonucleoprotein M isoform X2 {ECO:0000313|RefSeq:XP_025841514.1};
GN   Name=HNRNPM {ECO:0000313|RefSeq:XP_025841514.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025841514.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025841514.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025841514.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025841514.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025841514.1; XM_025985729.1.
DR   AlphaFoldDB; A0A3Q7R5S4; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd12657; RRM1_hnRNPM; 1.
DR   CDD; cd12659; RRM2_hnRNPM; 1.
DR   CDD; cd12661; RRM3_hnRNPM; 1.
DR   Gene3D; 3.30.70.330; -; 3.
DR   InterPro; IPR024666; HnRNP_M_PY-NLS.
DR   InterPro; IPR034990; hnRNPM_RRM3.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR23003; RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN; 1.
DR   Pfam; PF11532; HnRNP_M_NLS; 1.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 3.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR   PROSITE; PS50102; RRM; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   Ribonucleoprotein {ECO:0000313|RefSeq:XP_025841514.1};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176}.
FT   DOMAIN          71..149
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          204..281
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          686..762
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..58
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   763 AA;  81241 MW;  85CDCD7DE3671F4C CRC64;
     MAAGVEAAAE VATTETKMEE ESGAPGVPSG NGAPGPKGEG ERPTQNEKRK EKNIKRGGNR
     FEPYANPTKR YRAFITNIPF DVKWQSLKDL VKEKVGEVTY VELLMDAEGK SRGCAVVEFK
     MEESMKKAAE VLNKHSLSGR PLKVKEDPDG EHARRAMQKV MATTGGMGMG PGGPGMINIP
     PSILNNPNIP NEIIHALQAG RLGSTVFVAN LDYKVGWKKL KEVFSMAGVV VRADILEDKD
     GKSRGIGTVT FEQSIEAVQA ISMFNGQLLF DRPMHVKMDE RALPKGDFFP PERPQQLPHG
     LGGIGMGLGP GGQPIDANHL NKGIGMGNIG PAGMGMEGIG FGINKMGGME GPFGGGMENM
     GRFGSGMNMG RINEMERGMG GGFERDFARN KMGMSRSFGE PLGRGMEILS NALKRGEIIA
     KQGGGGGGGS VPGIERMGPG IDRIGGAGME RMGAGLGHGM DRVGSEIERM GLVMDRMGSV
     ERMGSGIERM GPLGLDHMAS SIERMGQTME RIGSGVERMG AGMGFGLERM AAPIDRVGQT
     IERMGSGVER MGPAIERMGL SMERMVPAGM GAGLERMGPV MDRMATGLER MGANNLERMG
     LERMGANSLE RMGLERMGAN SLERMGPAMG PALGAGIERM GLAMGGGGGA SFDRAIEMER
     GNFGGSFAGS FGGAGGHAPG VARKACQIFV RNLPFDFTWK MLKDKFNECG HVLYADIKME
     NGKSKGCGVV KFESPEVAER ACRMMNGMKL SGREIDVRID RNA
//