ID   A0A3Q7RD75_VULVU        Unreviewed;       986 AA.
AC   A0A3Q7RD75;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Leucine-rich repeat flightless-interacting protein 1 isoform X9 {ECO:0000313|RefSeq:XP_025840066.1};
GN   Name=LRRFIP1 {ECO:0000313|RefSeq:XP_025840066.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025840066.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025840066.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025840066.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025840066.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the LRRFIP family.
CC       {ECO:0000256|ARBA:ARBA00008275}.
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DR   RefSeq; XP_025840066.1; XM_025984281.1.
DR   AlphaFoldDB; A0A3Q7RD75; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.20.5.4090; -; 1.
DR   InterPro; IPR019139; LRRFIP1/2.
DR   PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR19212:SF5; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF09738; LRRFIP; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT   REGION          73..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          432..986
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          194..364
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        73..99
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..151
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..182
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        432..468
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        482..514
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        549..569
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        570..591
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        635..664
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        729..752
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        765..798
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        801..817
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        818..853
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        875..897
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   986 AA;  107671 MW;  9D178A24DC7F0BD1 CRC64;
     MSSPAAAQRG DMDCLSPEAQ KLAEARLAAK RAARAEAREI RMKELERQQK EIYQVQKKYY
     GLDTKWGDIE QWMEDSERYS RRSRRNTSAS DEDERMSVGS RGSLRLQPDS EYGGPYAWTN
     GYDGDLYGSQ SLGRRSGRVE ERPEKDFTEK GSRSLPGLSA ATLASLGGTS SRRGSGDTSI
     SVDTEASIRE IKELSELKDQ IQDVEGKYMQ GLKEMKDSLA EVEEKYKKAM VSNAQLDNEK
     TNFMYQVDTL KDMLLELEEQ LAESRRQYED KSKEFEREKH AHSILQFQFA EVKEALKQRE
     EMLEEIRQLQ QKQASYIREI SDLQETIEWK DKKIGALERQ KEFFDSIRSD RDDLREEVVM
     LKEELKKHGI VLNSEIATNG ETSETLNNVG HQGPSKITKE ELNALKTTGD GTLGRASEVE
     VKSEIVENVG KREILQNSEQ EQHREDPAQE CVDTEVLHPG ENAEDQKASE DSAPSLGVLA
     DATNEEQAQN QILENASFLE NTAQVESNEV TGTPDDRTGA PLEQSECLSE LADEIPCPGS
     GQDSCNASDI KKQSKESVEK QEDLKTSLGE DSTKPCQESA PLQTSDVGGL NSADPGEQGG
     NPTEGVVEAG LMGLGEQVGT GASGPPTCNN DNMSHDEECA AEAHTELDTS TGHALDKELS
     RQEAAEPPEL PGQRAAVDEE NDEKEDEERG LRDEEPGQTE VQDVPCCPAA ESSPQGATGL
     AVPDAKSKPL VTKEPEEEKS DQKGDALASS QKKIKNKKKK NKKKSPAPVE TLKDAKKELT
     FQNSDGSEVK EGEHAALSDT KPVVKTQNEV PESPKEKNIS GSSEKIDCPE NLKIELAEKL
     DQEDNDVNTK KGGKTADGDT LGLRGDTTQS SDMSASDKEL DEAVRKDDAK EDGAAHSSAP
     EPGHGGASSS VLPENEGPFK DTDDAPQTGS TEQHEMAEGP SQIVGKAVGN DHVASAGELG
     ASNSEGRGKP RGGSEKGKSN EECTMS
//