ID A0A3Q7RLD8_VULVU Unreviewed; 269 AA.
AC A0A3Q7RLD8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=SLA class II histocompatibility antigen, DQ haplotype C beta chain-like {ECO:0000313|RefSeq:XP_025846444.1};
GN Name=LOC112913861 {ECO:0000313|RefSeq:XP_025846444.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025846444.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025846444.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025846444.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025846444.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025846444.1; XM_025990659.1.
DR AlphaFoldDB; A0A3Q7RLD8; -.
DR STRING; 9627.ENSVVUP00000034796; -.
DR Ensembl; ENSVVUT00000045843; ENSVVUP00000034796; ENSVVUG00000025071.
DR KEGG; vvp:112913861; -.
DR OMA; LVTRYVY; -.
DR OrthoDB; 3785866at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
DR CDD; cd21001; IgC1_MHC_II_beta_HLA-DQ_I-A; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR000353; MHC_II_b_N.
DR PANTHER; PTHR19944:SF101; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DQ BETA 1 CHAIN; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00969; MHC_II_beta; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00921; MHC_II_beta; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 4: Predicted;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW MHC II {ECO:0000256|ARBA:ARBA00023182};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..269
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018759866"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..217
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 269 AA; 30495 MW; 73F4D79348F1087D CRC64;
MSGRMTLCIP RGFWTAAVMM ILEVLSIPGA EGRDSPQDFV YQFKGECYFT NGTERVRALT
KHIYNREEYV RFDSDVGEFR AVTELGRPDA EYWNGQKDVV DRVRAEVDTV CRHNYGVEES
FTVLRRVEPT VTISPSRTEV LNHHNLLVCA VTDFYPGQIK VRWFRNDQEQ TAGVVSTPLI
RNGDWTFQIL VMLEMTPQRG DVYTCHVEHA SLQSPITVQW RAQSESAQSK MLSGIGGFVL
GLIFLGLGLI IRHRSQKGSR ESPPAGLLH
//
