ID A0A3Q7RUV6_VULVU Unreviewed; 537 AA.
AC A0A3Q7RUV6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Metastasis-associated protein MTA3 isoform X2 {ECO:0000313|RefSeq:XP_025850092.1};
GN Name=MTA3 {ECO:0000313|RefSeq:XP_025850092.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025850092.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025850092.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025850092.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025850092.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025850092.1; XM_025994307.1.
DR AlphaFoldDB; A0A3Q7RUV6; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd11661; SANT_MTA3_like; 1.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR040138; MIER/MTA.
DR InterPro; IPR035170; MTA1_R1.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR PANTHER; PTHR10865:SF6; METASTASIS-ASSOCIATED PROTEIN MTA3; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF17226; MTA_R1; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1..91
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 92..203
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 210..262
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 60913 MW; FC8956D2CCE4C300 CRC64;
MLADKHAKEI EEESETTIEA DLTDKQKHQL KHRELFLSRQ YESLPATHIR GKCSVALLNE
TESVLSYLDK EDTFFYSLVY DPSVKTLLAD KGEIRVGPRY QADIPEMLLE GESDEREQSK
LEVKVWDPNS PLTDRQIDQF LVVARAVGTF ARALDCSSSV RQPSLHMSAA AASRDITLFH
AMDTLYRHSY DLSSAISVLV PVGGPVLCRD EMEEWSASEA SLFEEALEKY GKDFNDIRQD
FLPWKSLTSI IEYYYMWKTT DRYVQQKRLK AAEAESKLKQ VYIPTYKPNP NQISASNGKP
GAVNGAVGTT FQPQNPLLGR ACESCYATQS HQWYSWGPPN MQCRLCATCW LYWKKYGGLK
MPTQSEEEKL SPSPTTEDPR VRSHMSRQAM QGMPVRNTGS PKSAVKTRQA FFLHTTYFTK
FARQVCKNTL RLRQAARRPF VPINYAAIRA EYADRHAELS GSPLKSKSTR KPLACIIGYL
EIHPSKKPNV IRSTPSLQTP TTKRMLTTPN HTSLSILGKR NYSHHNGLDE LTCCVSD
//
