ID A0A3Q7RV73_VULVU Unreviewed; 737 AA.
AC A0A3Q7RV73;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Semaphorin-4F isoform X2 {ECO:0000313|RefSeq:XP_025850242.1};
GN Name=SEMA4F {ECO:0000313|RefSeq:XP_025850242.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025850242.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025850242.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025850242.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025850242.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR RefSeq; XP_025850242.1; XM_025994457.1.
DR AlphaFoldDB; A0A3Q7RV73; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR045791; Sema4F_C.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF72; SEMAPHORIN-4F; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF19428; Sema4F_C; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..737
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018584636"
FT TRANSMEM 626..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..477
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 663..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 80121 MW; 8DC3E73937A021F8 CRC64;
MLASATPPLP GSQPPPASPF PLLLLAVLSG PASGRVPRSV PRTSLPISEA DSYLTRFSVP
QTYNYSVLLV DPASHTLYVG TRDTVFALSL PFSGERPRRI DWMVPEAHRQ NCRKKGKKED
VSSFQQVERL ENGRGKCPFE PAQRSAAVMA GGVLYAATVK NYLGTEPIIS RAVGRTEDWI
RTETLPSWLN APAFAAAMAL SPAEWGDEDG DDEIYFFFTE TSRAFDSYER IKVPRVARVC
AGDLGGRKTL QHRWTTFLKA DLLCPGPEHG RASSILQDVA ILRPEHRSET PIFYGIFSSQ
WEGAAISAVC AFRPQDIRTV LNGPFRELKH DCNRGLPVMD NDVPQPRPGE CITNNMKLQQ
FGSSLSLPDR VLTFIRDHPL MDRPVFPTDD HPLLVTTDTA YLRVVAHRVT SLSGKEYDVL
YLGTEDGHLH RAVRIGAQLS VLEDLALFPE PQPVESMKLY QNWLLVGSRT EVTQVNTTNC
GRLQSCSECI LAQDPVCAWS FQLDACVAHA GEHGRLVQDI ESADVSSLCP REPGEHPVVF
EVPVATAAHV VLPCSPSSAW ASCVWHQPGG VTALTPRRDG LEVVVTPGAM GAYACECQEG
GAARVVAAYS LVWGSRRSPA SQAHTVGAGL AGFVLGVLAA SLTLLLIGRR QQRRRQRELL
ARDKVGLDLG APPSGTTSYS QDPPSPSPED ERLPLALAKR GSGFGGFPPP FLLDPCPSPA
HIRLTGAPLA TCDETSI
//
