ID A0A3Q7RYG8_VULVU Unreviewed; 159 AA.
AC A0A3Q7RYG8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Keratin-associated protein 4-11-like isoform X1 {ECO:0000313|RefSeq:XP_025851977.1};
GN Name=LOC112918025 {ECO:0000313|RefSeq:XP_025851977.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025851977.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025851977.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025851977.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025851977.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: In the hair cortex, hair keratin intermediate filaments are
CC embedded in an interfilamentous matrix, consisting of hair keratin-
CC associated proteins (KRTAP), which are essential for the formation of a
CC rigid and resistant hair shaft through their extensive disulfide bond
CC cross-linking with abundant cysteine residues of hair keratins. The
CC matrix proteins include the high-sulfur and high-glycine-tyrosine
CC keratins. {ECO:0000256|ARBA:ARBA00003327}.
CC -!- SUBUNIT: Interacts with hair keratins. {ECO:0000256|ARBA:ARBA00011662}.
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DR RefSeq; XP_025851977.1; XM_025996192.1.
DR AlphaFoldDB; A0A3Q7RYG8; -.
DR KEGG; vvp:112918025; -.
DR OrthoDB; 5267131at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR InterPro; IPR002494; KAP.
DR PANTHER; PTHR23262; KERATIN ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23262:SF183; KERATIN-ASSOCIATED PROTEIN 4-11-RELATED; 1.
DR Pfam; PF13885; Keratin_B2_2; 2.
PE 4: Predicted;
KW Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640}.
SQ SEQUENCE 159 AA; 16447 MW; CA394E2CDF2E30D9 CRC64;
MVNSCCGSVC SDQSCGQDCC ISSCCRPTCC QPTCCRTTCC RPSCCVSSCC RPTCCQTTCC
RTTCCRPSCC VSSCCRPSCS GSSCCGSSCC RPSCCISSCC RPSCCGSSSC GSSCCRPSCC
PSCCLRPVCG RVSCHSTCYR PTCVISTCPR PMCCASSCC
//
