ID   A0A3Q7S1H8_VULVU        Unreviewed;       681 AA.
AC   A0A3Q7S1H8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=G-protein-signaling modulator 2 isoform X1 {ECO:0000313|RefSeq:XP_025852119.1};
GN   Name=GPSM2 {ECO:0000313|RefSeq:XP_025852119.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025852119.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025852119.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025852119.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025852119.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GPSM family.
CC       {ECO:0000256|ARBA:ARBA00006600}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_025852119.1; XM_025996334.1.
DR   AlphaFoldDB; A0A3Q7S1H8; -.
DR   STRING; 9627.ENSVVUP00000000895; -.
DR   Ensembl; ENSVVUT00000001373; ENSVVUP00000000907; ENSVVUG00000000788.
DR   KEGG; vvp:112918244; -.
DR   OMA; PEDRSFH; -.
DR   OrthoDB; 4190321at2759; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR003109; GoLoco_motif.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45954:SF3; G-PROTEIN-SIGNALING MODULATOR 2; 1.
DR   PANTHER; PTHR45954; LD33695P; 1.
DR   Pfam; PF02188; GoLoco; 4.
DR   Pfam; PF13374; TPR_10; 1.
DR   Pfam; PF13424; TPR_12; 2.
DR   Pfam; PF13176; TPR_7; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00390; GoLoco; 4.
DR   SMART; SM00028; TPR; 7.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50877; GOLOCO; 4.
DR   PROSITE; PS50005; TPR; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          62..95
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          242..275
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   681 AA;  76347 MW;  A910D59149774411 CRC64;
     MEENLISMRE DHSFHVRYRM EASCLELALE GERLCKSGDC RAGVSFFEAA VQVGTEDLKT
     LSAIYSQLGN AYFYLHDYAK ALEYHHHDLT LARTIGDQLG EAKASGNLGN TLKVLGNFDE
     AVVCCQRHLD ISRELNDKVG EARALYNLGN VYHAKGKSFG CPGPQDIGEF PEEVRNALQA
     AVDYYEENLS LVTALGDRAA QGRAFGNLGN THYLLGNFRD AVIAHEQRLL IAKEFGDKAA
     ERRAYSNLGN AYIFLGEFET ASEYYKKTLL LARQLKDRAV EAQSCYSLGN TYTLLQDYEK
     AIDYHLKHLA IAQELNDRIG EGRACWSLGN AYTALGNHDQ AMHFAEKHLE ISREVGDRSG
     ELTARLNLSD LQMVLGLSYS TNNSIMSENI EIDNSLHGAR PKFGRRHSME NMELMKLTPE
     KVQNWNSEIL AKQKPLIAKP SAKLLFVNRL KGKKCKTNSS TKVLQDASNS IDRRIPNSQR
     KVSTDTIGDE GFFDLVSRFQ SNRMDDQRCC LQEQSCGPAS TAASSTPPRV MLKTPSVSMV
     SPNTDEFLDL LASSQSRRLD DQRASFSNLP GLRLTQNNNK SVLGHLMTND NKEPDEDFFD
     ILVKCQGSRL DDQRCAPPPA TTKGPTVPDE DFFSLILRSQ AKRMDEQRVL LQRDQNRDTE
     FGLKDLFQSK ALLEFKNTGK K
//