ID   A0A3Q7S1J0_VULVU        Unreviewed;       922 AA.
AC   A0A3Q7S1J0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=WD repeat-containing protein 47 isoform X4 {ECO:0000313|RefSeq:XP_025852137.1, ECO:0000313|RefSeq:XP_025852138.1};
GN   Name=WDR47 {ECO:0000313|RefSeq:XP_025852137.1,
GN   ECO:0000313|RefSeq:XP_025852138.1, ECO:0000313|RefSeq:XP_025852139.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025852139.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025852137.1, ECO:0000313|RefSeq:XP_025852138.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025852137.1,
RC   ECO:0000313|RefSeq:XP_025852138.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025852137.1,
RC   ECO:0000313|RefSeq:XP_025852138.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025852137.1; XM_025996352.1.
DR   RefSeq; XP_025852138.1; XM_025996353.1.
DR   RefSeq; XP_025852139.1; XM_025996354.1.
DR   OrthoDB; 76273at2759; -.
DR   Proteomes; UP000286640; Unplaced.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR006595; CTLH_C.
DR   InterPro; IPR006594; LisH.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   InterPro; IPR040067; WDR47.
DR   PANTHER; PTHR19863; NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG; 1.
DR   PANTHER; PTHR19863:SF5; WD REPEAT-CONTAINING PROTEIN 47; 1.
DR   Pfam; PF17814; LisH_TPL; 1.
DR   Pfam; PF00400; WD40; 6.
DR   SMART; SM00668; CTLH; 1.
DR   SMART; SM00667; LisH; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50897; CTLH; 1.
DR   PROSITE; PS50896; LISH; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   DOMAIN          45..102
FT                   /note="CTLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50897"
FT   REPEAT          658..688
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          754..794
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          799..840
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          841..875
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          887..922
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          392..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          502..595
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        392..414
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        502..583
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   922 AA;  102383 MW;  FDF98ECE5E262813 CRC64;
     MTAEETVNVK EVEIIKLILD FLNSKKLHIS MLALEKESGV INGLFSDDML FLRQLILDGQ
     WDEVLQFIQP LECMEKFDKK RFRYIILKQK FLEALCVNNA MSAEDEPQHL EFTMQEAVQC
     LHALEEYCPS KDDYSKLCLL LTLPRLTNHA EFKDWNPSTA RVHCFEEACV MVAEFIPADR
     KLSEAGFKAS NNRLFQLVMK GLLYECCVEF CQSKATGEEI TESEVLLGID LLCGNGCDDL
     DLSLLSWLQN LPSSVFSCAF EQKMLNIHVD KLLKPTKAAY ADLLTPLISK LSPYPSSPMR
     RPQSADAYMT RSLNPALDGL TCGLTSHDKR ISDLGNKTSP MSHSFANFHY PGVQNLSRSL
     MLENTECHSI YEESPERSDT PVEAQRPISS EILGQSSVSE KESANGTQNP GPAKQEKNEL
     RDSTEQFQEY YRQRLRYQQH LEQKEQQRQI YQQMLLEGGV NQEDGPDQQQ NLTEQFLNRS
     IQKLGELNIG MDSLGNEVSA LNQQCNGSKN NGSNNNSLTN FVTPPQDSSQ RITHDASNIH
     TSTPSNPGST NHIPFLEESP SGNQISSEHS VSKPALGDSS GNLSRSRGEE DDKSKKQFVC
     INTLEDTQAV RAVAFHPGGG LYAVGSNSKT LRVCAYPEVI DPSACDIPKQ PVVRFKRNKH
     HKGSIYCVAW SPCGQLLATG SNDKYVKVLP FNAETCNATV SGPDLEFSMH DGTIRDLAFM
     EGPESGGAIL ISAGAGDCNI YTTDCQRGQG LHALSGHTGH ILALYTWSGW MIASGSQDKT
     VRFWDLRVPS CVRVVGTTFH GTGSAVASVA VDPSGRLLAT GQEDSSCMLY DIRGGRMVQS
     YHPHSSDVRS VRFSPGAHYL LTGSYDMKIK VTDLQGDLTK QLPIMVVGEH KDKVIQCRWH
     TQDLSFLSSS ADRTVTLWTY NG
//