ID   A0A3Q7S5U5_VULVU        Unreviewed;      1092 AA.
AC   A0A3Q7S5U5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=ELKS/Rab6-interacting/CAST family member 1 isoform X3 {ECO:0000313|RefSeq:XP_025851248.1};
GN   Name=ERC1 {ECO:0000313|RefSeq:XP_025851248.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025851248.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025851248.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025851248.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025851248.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_025851248.1; XM_025995463.1.
DR   AlphaFoldDB; A0A3Q7S5U5; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0098793; C:presynapse; IEA:UniProt.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 1.20.5.2440; -; 1.
DR   InterPro; IPR019323; ELKS/CAST.
DR   InterPro; IPR037245; FIP-RBD_C_sf.
DR   InterPro; IPR019018; Rab-bd_FIP-RBD.
DR   PANTHER; PTHR18861; ELKS/RAB6-INTERACTING/CAST PROTEIN; 1.
DR   PANTHER; PTHR18861:SF1; ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1; 1.
DR   Pfam; PF10174; Cast; 1.
DR   Pfam; PF09457; RBD-FIP; 1.
DR   SUPFAM; SSF144270; Eferin C-derminal domain-like; 1.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
DR   PROSITE; PS51511; FIP_RBD; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT   DOMAIN          1022..1084
FT                   /note="FIP-RBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51511"
FT   REGION          1..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          559..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          775..812
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          151..178
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          215..249
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          336..418
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1038..1065
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        31..55
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1092 AA;  125321 MW;  68C24C76529A14C2 CRC64;
     MYGSARSVGK VEPSNQSPGR SPRLPRSPRL GHRRTNSTGG SSGSSVGGGG GKTLSMENIQ
     SLNAAYATSG PMYLSDHENV GSETPKSTMT LGRSGGRLPY GVRMTAMGSS PNIASSGVAS
     DTIAFGEHHL PPVSMASTVP HSLRQARDNT IMDLQTQLKE VLRENDLLRK DVEVKESKLS
     SSMNSIKTFW SPELKKERAL RKDEASKITI WKEQYRVVQE ENQHMQMTIQ ALQDELRIQR
     DLNQLFQQDS SSRTGEPCVT ELTEENFQRL HAEHERQAKE LFLLRKTLEE MELRIETQKQ
     TLNARDESIK KLLEMLQSKG LSAKATEEDH ERTRRLAEAE MHVHHLESLL EQKEKENSML
     REEMHRRFEN APDSAKTKAL QTVIEMKDSK ISSMERGLRD LEEEIQMLKS NGALSTEERE
     EEMKQMEVYR SHSKFMKNKI GQVKQELSRK DTELLALQTK LETLTNQFSD SKQHIEVLKE
     SLTAKEQRAA ILQTEVDALR LRLEEKETML NKKTKQIQDM AEEKGTQAGE IHDLKDMLDV
     KERKVNVLQK KIENLQEQLR DKEKQMSSLK ERVKSLQADT TNTDTALTTL EEALAEKERT
     IERLKEQRDR DEREKQEEID NYKKDLKDLK EKVSLLQGDL SEKEASLLDL KEHASSLASS
     GLKKDSRLKT LEIALEQKKE ECLKMESHLK KAHEATLEAR ASPEMSDRIQ QLEREISRYK
     DESSKAQAEV DRLLEILKEV ENEKNDKDKK IAELESLTSR QVKDQNKKVA NLKHKEQVEK
     KKSAQMLEEA RRREDNLNDS SQQLQDSLRK KDDRIEELEE ALRESVQITA EREMVLAQEE
     SARTSAEKQV EELLMAMEKV KQELESMKAK LSSTQQSLAE KETHLTNLRA ERRKHLEEVL
     EMKQEALLAA ISEKDANIAL LELSSSKKKT QEEVAALKRE KDRLVQQLKQ QTQNRMKLMA
     DNYEDDHFKS SHSNQTNHKP SPDQIIQPLL ELDQNRSKLK LYIGHLTALC HDRDPLILRG
     LTPPASYNLD DDQAAWENEL QKMTQEQLQN ELEKGERDNA ELQEFANAIL QQIADHCPDI
     LEQVVNALEE SS
//