ID A0A3Q7S645_VULVU Unreviewed; 615 AA.
AC A0A3Q7S645;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Semaphorin-4F isoform X5 {ECO:0000313|RefSeq:XP_025850246.1};
GN Name=SEMA4F {ECO:0000313|RefSeq:XP_025850246.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025850246.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025850246.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025850246.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025850246.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR RefSeq; XP_025850246.1; XM_025994461.1.
DR AlphaFoldDB; A0A3Q7S645; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR045791; Sema4F_C.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF72; SEMAPHORIN-4F; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF19428; Sema4F_C; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..615
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018761846"
FT TRANSMEM 504..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..355
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 541..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 66626 MW; 75EB9F382AE587A6 CRC64;
MLASATPPLP GSQPPPASPF PLLLLAVLSG PASGRVPRSV PRTSLPISEA DSYLTRFSVP
QTYNYSVLLV DPASHTLYVG TRDTVFALSL PFSGERPRRI DWMVPEAHRQ NCRKKGKKEG
DLGGRKTLQH RWTTFLKADL LCPGPEHGRA SSILQDVAIL RPEHRSETPI FYGIFSSQWE
GAAISAVCAF RPQDIRTVLN GPFRELKHDC NRGLPVMDND VPQPRPGECI TNNMKLQQFG
SSLSLPDRVL TFIRDHPLMD RPVFPTDDHP LLVTTDTAYL RVVAHRVTSL SGKEYDVLYL
GTEDGHLHRA VRIGAQLSVL EDLALFPEPQ PVESMKLYQN WLLVGSRTEV TQVNTTNCGR
LQSCSECILA QDPVCAWSFQ LDACVAHAGE HGRLVQDIES ADVSSLCPRE PGEHPVVFEV
PVATAAHVVL PCSPSSAWAS CVWHQPGGVT ALTPRRDGLE VVVTPGAMGA YACECQEGGA
ARVVAAYSLV WGSRRSPASQ AHTVGAGLAG FVLGVLAASL TLLLIGRRQQ RRRQRELLAR
DKVGLDLGAP PSGTTSYSQD PPSPSPEDER LPLALAKRGS GFGGFPPPFL LDPCPSPAHI
RLTGAPLATC DETSI
//
