ID A0A3Q7S9T6_VULVU Unreviewed; 1168 AA.
AC A0A3Q7S9T6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=C-Jun-amino-terminal kinase-interacting protein 4 isoform X12 {ECO:0000313|RefSeq:XP_025851726.1};
GN Name=SPAG9 {ECO:0000313|RefSeq:XP_025851726.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025851726.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025851726.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025851726.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025851726.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025851726.1; XM_025995941.1.
DR AlphaFoldDB; A0A3Q7S9T6; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR039911; JIP3/JIP4.
DR InterPro; IPR032486; JIP_LZII.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13886:SF2; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4; 1.
DR PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR Pfam; PF16471; JIP_LZII; 1.
DR Pfam; PF19056; WD40_2; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51777; RH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Kinase {ECO:0000313|RefSeq:XP_025851726.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Transferase {ECO:0000313|RefSeq:XP_025851726.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 347..418
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 94..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1087..1113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 574..601
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 106..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..447
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1168 AA; 127462 MW; E2A35ABFB9600F4E CRC64;
MSPGCMLLFV FGFVGGAVVI NSAILVSLSV LLLVHFSIST GVPALTQNLP RILRKERPIS
LGIFPLPAGD GLLTPDTQKG GETPGSEQWK FQELSQPRSH TSLKDELSDV SQGGSKATTP
ASTAASDVAT IPTDTPLKED NEGFVKVADT PNKSEISKHI EVQVAQETRN VSTGSAENEE
KSEVQAIIES TPELDMDKDL SGYKGSSTPT KGIENKAFDR NTESLFEELS SAGSGLIGDV
DEGADLLGEY SGMGREVENL ILENTQLLET KHALNVVKND LIAKVDELTC EKDVLQGELE
AVKQAKLKLE EKNKELEEEL RKARAEAEDA RQKAKDDDDS DIPTAQRKRF TRVEMARVLM
ERNQYKERLM ELQEAVRWTE MIRASRENPA MQEKKRSSIW QFFSRLFSSS SNTTKKPEPP
VNLKYNAPTS HVTPSVKKRS STLSQLPGDK SKAFDFLSEE TEASLASRRE QKREQYRQVK
AHVQKEDGRV QAFGWSLPQK YKQVTNGQGE NKMKNLPVPV YLRPLDEKDT SMKLWCAVGV
NLSGGKTRDG GSVVGASVFY KDVAGLDTEG SKQRSASQSS LDKLDQELKE QQKELKNQEE
LSSLVWICTS THSATKVIII DAIQPGNILD SFTVCNSHVL CIASVPGARE TDYPAGEELS
ESGQVDKASL CGSMTSNSSA ETDSLLGGIT VVGCSTEGVT AAATSPSTNG ASPVTENPPE
KEAENSEVDE NIPTAEEATE ATEGNAGSAE DTVDTSQPGV YTEHVFTDPL GVQIPEDLSP
VYQSSNDSDA YKDQLSVLPN EQDLVREEAQ KMSSLLPTMW LGAQNGCLYV HSSVAQWRKC
LHSIKLKDSI LSIVHVKGIV LVALADGTLA IFHRGVDGQW DLSNYHLLDL GRPHHSIRCM
TVVHDKVWCG YRNKIYVVQP KAMKIEKSFD AHPRKESQVR QLAWVGDGVW VSIRLDSTLR
LYHAHTYQHL QDVDIEPYVS KMLGTGKLGF SFVRITALMV SCNRLWVGTG NGVIISIPLT
ETNKTSGAPG NRPGSVIRVY GDENSDKVTP GTFIPYCSMA HAQLCFHGHQ DAVKFFVAVP
GQVISPQSGS SGTDLTGDKA GPSTPEPGSQ TPLKSMLVIS GGEGYIDFRM GDEGGESELL
GEDLPLEPSV AKAERSHLIV WQVMYGSE
//
