ID A0A3Q7SHC4_VULVU Unreviewed; 756 AA.
AC A0A3Q7SHC4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Zinc finger protein 471 isoform X1 {ECO:0000313|RefSeq:XP_025841144.1, ECO:0000313|RefSeq:XP_025841145.1};
GN Name=LOC112909435 {ECO:0000313|RefSeq:XP_025841144.1,
GN ECO:0000313|RefSeq:XP_025841145.1, ECO:0000313|RefSeq:XP_025841148.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025841145.1};
RN [1]
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025841144.1,
RC ECO:0000313|RefSeq:XP_025841148.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025841144.1,
RC ECO:0000313|RefSeq:XP_025841148.1};
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025841145.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025841145.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025841145.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_025841144.1; XM_025985359.1.
DR RefSeq; XP_025841145.1; XM_025985360.1.
DR RefSeq; XP_025841148.1; XM_025985363.1.
DR STRING; 9627.ENSVVUP00000008773; -.
DR KEGG; vvp:112909435; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 18.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24393; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24393:SF167; ZINC FINGER PROTEIN 345-RELATED; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 17.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 18.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 10.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 18.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 18.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 14..85
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 206..233
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 234..261
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 262..289
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 290..317
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 318..345
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 346..374
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 375..402
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 403..430
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 431..458
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 459..486
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 487..514
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 515..542
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 543..570
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 571..598
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 599..626
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 627..654
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 655..682
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 683..710
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 756 AA; 87762 MW; 64E1929166E61D28 CRC64;
MTVELVKAIS QDLVTFKDVA IDFSQDEWEW LNPVQRNLYK NMMLENYQNL VSLGLCISKP
YVISLLEQGK EPWEMKTEMT RSPFPDSGST YETQELPLKH FMYDNVLMER ITRYGLECST
FRKNWKCEDI FERQLVSQET FIRQEVITHN KTLTKEIDRK YNKSGKFVYL DNVEENVYNH
KLDKKSFPQN SVVVKHKKVY AGKKLFKCNE CEKTFTHSSS LTVHQRIHTG EKPYECKECG
KAFNQSQHLV QHHRIHTGEK LFECKECKKA FSQNVHLIQH QRIHTGEKPY KCMECRKAFS
QPAHLAQHQR IHTGEKPYEC KECGKAFSDG SSFARHQRCH TGKRPYECIE CEKAFRQNTS
LIRHWRYYHT GEKPFDCIDC GKAFSDHIGL IQHRRIHTGE KPYKCQVCGK TFSYGSSLTV
HQRIHTGEKP YECVVCGKAF SHHASLTQHQ RVHSGEKPYE CKECGKAFRQ SIHLASHLRI
HTGEKPYECK ECGKAFSISS QLATHQRIHT GEKPYECNEC GKAFNQRAHL AQHHKIHTGE
KPYECNECGK AFSQTTRLIQ HQRIHTGEKP YKCSECGKAF SDSSSRSQHR RLHTGQRPYE
CVECEKAFRT KSSLICHQRC HTGEKPYECS VCGKAFSHRQ SLTVHQRIHS GEKPYECHEC
GKTFSQIGHL NLHRRIHTGE RSYECKECGK VFRQSVHLTH HQKVHAVESS QASSSSSPPV
SPSPMNISAR YFWNSSTFNL HCPTPKHSHF TCTVPI
//
