ID   A0A3Q7SHD2_VULVU        Unreviewed;       512 AA.
AC   A0A3Q7SHD2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Adenylate kinase isoenzyme 5 isoform X2 {ECO:0000313|RefSeq:XP_025860519.1};
GN   Name=AK5 {ECO:0000313|RefSeq:XP_025860519.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025860519.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025860519.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025860519.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025860519.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the adenylate kinase family.
CC       {ECO:0000256|ARBA:ARBA00007220, ECO:0000256|RuleBase:RU003330}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_025860519.1; XM_026004734.1.
DR   AlphaFoldDB; A0A3Q7SHD2; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004017; F:adenylate kinase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046034; P:ATP metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd01428; ADK; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   HAMAP; MF_00235; Adenylate_kinase_Adk; 2.
DR   InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR   InterPro; IPR033690; Adenylat_kinase_CS.
DR   InterPro; IPR006267; AK1/5.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR01360; aden_kin_iso1; 1.
DR   PANTHER; PTHR23359:SF79; ADENYLATE KINASE ISOENZYME 5; 1.
DR   PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR   Pfam; PF00406; ADK; 2.
DR   PRINTS; PR00094; ADENYLTKNASE.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00113; ADENYLATE_KINASE; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU003330};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003330}.
SQ   SEQUENCE   512 AA;  57266 MW;  C3059F7D9404079D CRC64;
     MCSKPEDPVE YLESCLQKVK ELGGCDKVKW DTFVSQEKKT LPPLNGGQSR RSFLRNESDT
     DLSETAELIE EYEVFDPTRP RPKIILVIGG PGSGKGTQSL KIAERYGFQY ISVGELLRKK
     IHSTSSNRKW SLIAKIITTG ELAPQETTIT EIKQKLMQIP DEEGIVIDGF PRDVAQALSF
     EDQICTPDLV VFLACANQRL KERLLKRAEQ QGRPDDNLKA TQRRLMNFKQ NAAPLVKYFQ
     EKGLIMTFDA DRDEDEVFYD ISMAVDSKLF PNKEAAAGSS DLDPSMMLDT GETIDTGSDY
     EDQGDDQLNV FGEDTMGGFM EDLRKCKIIF MIGGPGSGKG TQCEKLVEKY GFTHLSTGEL
     LRNELSSESE RSKLIRDIMD RGDPVPSGII LELLKEAMGA SLSDTRGFLI DGYPQEVKQG
     EEFGRRIGDP HLVICMDCSA DTMTNRLLQR SQGSPSVEDN TTTIAKRLET YYRASIPVIA
     YYETKTQLHK VNAEGTPEEV FLQLCTAIDS IF
//