ID A0A3Q7SJH1_VULVU Unreviewed; 1662 AA.
AC A0A3Q7SJH1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Microtubule cross-linking factor 1 isoform X2 {ECO:0000313|RefSeq:XP_025861724.1};
GN Name=MTCL1 {ECO:0000313|RefSeq:XP_025861724.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025861724.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025861724.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025861724.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025861724.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025861724.1; XM_026005939.1.
DR Ensembl; ENSVVUT00000021039; ENSVVUP00000015992; ENSVVUG00000011763.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR InterPro; IPR027882; DUF4482.
DR InterPro; IPR027881; SOGA.
DR PANTHER; PTHR15742:SF3; MICROTUBULE CROSS-LINKING FACTOR 1; 1.
DR PANTHER; PTHR15742; UNCHARACTERIZED; 1.
DR Pfam; PF14818; DUF4482; 1.
DR Pfam; PF11365; SOGA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT DOMAIN 931..1054
FT /note="DUF4482"
FT /evidence="ECO:0000259|Pfam:PF14818"
FT REGION 398..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 760..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1105..1169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1225..1256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1363..1392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1411..1458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1480..1546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1565..1662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1..64
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 93..141
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 177..204
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 232..266
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 292..326
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 664..695
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 952..979
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 402..443
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..775
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1130..1149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1627..1641
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1662 AA; 185719 MW; E50D79A7E577CEA1 CRC64;
MEELRSENDY LKDELDELRA EMEEMRDSYL EEDVYQLQEL RRELDRAHKN CRILQYRLRK
AEQKSLKVAE TGQVDGELIR SLEQDLKVAK DVSVRLHHEL ETVEEKRAKA EDENESLRQQ
MIEVEISKQA LQNELERLKE SSLKRRGNRE TYKEKKTFNQ DDSADLKCQL QFAKEEGSLM
RKKMAKLGKE KDELEQELQK YKALYGDVDS PLPTGEAGGP PSTREAELKL RLKLVEEEAN
ILGRKIVELE VENRGLKAEM EDMRLQYERE GTGRDHITGI PTSPFGDSLE SSTELRRHLQ
FVEEEAELLR RSISEIEDHN RQLTHELNKF KFEPRPEPGW LADGAGKGVG SGAPLQEELK
SARLQINELS GKVLKLQYEN RVLLSNVQRY DLAAHLGLRA PSPRDSDADS DQGKKESDGE
EGRQPQPKRE GPIGGESDSE EMCEKTSGFG SGKPSEASEP CPAELLRARE DTECLASIKH
EAERLERTVE RLITDTAGFG DDVGLLGSGE ALPGPDIQGA GGTGEGGKKE PPLLGTINSR
MKAFRKELQA FLEQVNRIGD GLRERLEGLS PLPHLTESSS FLSTVTSVSR DSPVGNLGKE
LVPDLQSKLR GQLEWQPGQE CGDEPEQLHR RADGDVGSCR QGGQSCFSLE LRGPPVLPEQ
SVSLEELQGQ LAQATRLHQE ETEKFTNKIR KMEEEHLYAL RWKELEMHSL ALQNTLHEQT
WSDERNLMQQ ELRSMKQNIF LFYVKLRWLL RHWRQGKQME EEGEDFTENE HPETLPRLGE
LGVQGDPKGD GPDQDDNSPG CSFPLGDHPP HSPVQIGDHG SRLQPTHGRQ LHRQVVENQQ
LFGALKSLLE DLRAELREDE HARRRLQQQY ASDKAAWDVE WAALTCRLEQ LEEKTEKNLG
EAGSSTDSKG AFKKEREMHQ KLLTDSHGLV MDLRWQIHHS EKNWSREKVE LLSRLDRDRQ
EWEQQKKELL WRIEQLQKEN SPRRSGSFLC DQKEGTIRPF AHPGSPRMPR PLGMWSCADT
DSTPFEDRPL SKLKESDRCS ARENLYLDAL SLDDEPEEPP ARGPQREFRN CLPQEEENHK
GNLQRAVSVS SMSEFQRLMD VSPFLPEKGV PATSSKEDIT PPLSPDDLKY IEEFNSKNWD
ERPPEPWADR TEGGRAGSEA GAEPFPDSSW YLTTSVTMTT DTMTSPEHCQ KQPLRSPMCT
EQAGVRVLHS PPAVRRMDGI VVAGSEGKGR AEPECPFPTS RARGGTGDTK GGPSEHVLSR
WPCAPSRHPR DYVEGGLRPL ESALCAPLGF ASSLHGLQMS KNMSDDMKEV AFSVRNAICS
GPPKPPLKDM ACQTNGSRTT GTQTVQTITI GLQTEALRGS AVTSSPHKCL TPKAGGGATP
ASSPSRGLRS RQMAPAIEKV QAKFERTCCS PKYGSPKLQR KPLPKAEPPN SRTSLGLAPK
GCSESAWARS TTTRESPVHT AINDGLSSLF NIIDHSPVVQ DPFQKGTRAG SRSRSAEPRP
ELGPGQETGP SSRGRSPSPI GAGSETWREE GGEGTPLRQD LSAPPGYTFT ENVARILNKK
LLEHALKEER RQAPHGPPSL NSDSHMGETI KAEPGSIEEL PCSALAPSLE PCFSRPERPA
NRRLPSRWAS HSPTASLAQS PGDPASLEEL GDEEPPGEKT HL
//
