ID A0A3Q7SM74_VULVU Unreviewed; 360 AA.
AC A0A3Q7SM74;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=cAMP-responsive element modulator {ECO:0000256|ARBA:ARBA00039496};
GN Name=CREM {ECO:0000313|RefSeq:XP_025856601.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025856601.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025856601.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025856601.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025856601.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the bZIP family.
CC {ECO:0000256|ARBA:ARBA00007163}.
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DR RefSeq; XP_025856601.1; XM_026000816.1.
DR AlphaFoldDB; A0A3Q7SM74; -.
DR STRING; 9627.ENSVVUP00000000945; -.
DR OrthoDB; 3137625at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd14690; bZIP_CREB1; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR003102; CREB1-like_pKID.
DR InterPro; IPR001630; Leuzip_CREB.
DR PANTHER; PTHR45879:SF4; CAMP-RESPONSIVE ELEMENT MODULATOR; 1.
DR PANTHER; PTHR45879; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR Pfam; PF02173; pKID; 1.
DR PRINTS; PR00041; LEUZIPPRCREB.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
DR PROSITE; PS50953; KID; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 104..163
FT /note="KID"
FT /evidence="ECO:0000259|PROSITE:PS50953"
FT DOMAIN 302..353
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 23..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 327..354
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 360 AA; 38794 MW; 42A269D3DFF7EC35 CRC64;
MSKCSRKKYI KTNLRQMTMD TIESRQDGSV TDSVAENESA HMQNQTGQNS IPTLTQVSVA
GSGTGRGSPA VTLVQLPSGQ TVHVQGVIQT PQPSVIQSPQ IQTVQVATIA ETDESAESEG
VIDSHKRREI LSRRPSYRKI LNELSSDVPG VPKIEEEKSE EEGTPPNIAT MAVPTSIYQT
STGQYIAIAQ GGTIQISNPG SDGVQGLQAL TMTNSGAPPP GATIVQYAAQ SADGTQQFFV
PGSQVVVQDE ETELAPSHMA AATGDMPTYQ IRAPTTALPQ GVVMAASPGS LHSPQQLAEE
ATRKRELRLM KNREAAKECR RRKKEYVKCL ESRVAVLEVQ NKKLIEELET LKDICSPKTD
//
