ID A0A3Q7SNH5_VULVU Unreviewed; 323 AA.
AC A0A3Q7SNH5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC6 {ECO:0000256|PIRNR:PIRNR028763};
DE Short=RNA polymerase III subunit C6 {ECO:0000256|PIRNR:PIRNR028763};
GN Name=POLR3F {ECO:0000313|RefSeq:XP_025858138.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025858138.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025858138.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025858138.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025858138.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific peripheric component of RNA polymerase III which synthesizes
CC small RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|PIRNR:PIRNR028763}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR028763}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase
CC subunit family. {ECO:0000256|ARBA:ARBA00011038,
CC ECO:0000256|PIRNR:PIRNR028763}.
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DR RefSeq; XP_025858138.1; XM_026002353.1.
DR AlphaFoldDB; A0A3Q7SNH5; -.
DR SMR; A0A3Q7SNH5; -.
DR KEGG; vvp:112922721; -.
DR OrthoDB; 930780at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR007832; RNA_pol_Rpc34.
DR InterPro; IPR016049; RNA_pol_Rpc34-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12780:SF1; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6; 1.
DR PANTHER; PTHR12780; RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED; 1.
DR Pfam; PF05158; RNA_pol_Rpc34; 1.
DR PIRSF; PIRSF028763; RNA_pol_Rpc34; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|PIRNR:PIRNR028763,
KW ECO:0000313|RefSeq:XP_025858138.1};
KW Nucleus {ECO:0000256|PIRNR:PIRNR028763};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR028763}.
SQ SEQUENCE 323 AA; 36462 MW; E0FB57389EC9C7B2 CRC64;
MAEVKVKVQP PDADPVEVEN RIIELCHQFP HGITDQVIQN EMPHIEAQQR AVAINRLLSM
GQLDLLRSNT GLLYRIKDSQ NAGPVSFFLS KMKGSDNQEK LVYQIIEDAG NKGIWSRDIR
YKSNLPLTEI NKILKNLESK KLIKAVKSVA ASKKKVYMLY NLQPDRSVTG GAWYSDQDFE
SEFVEVLNQQ CFKFLQTKAE TARESKQNPM IQRNSSFASS HEVWKYICEL GISKVELSME
DIETILNTLI YDGKVEMTII AAKEGTVGSV DGHMKLYRAV NPIIPPTGLV RAPCGLCPVF
DDCHEGGEIS PSNCIYMTEW LEF
//
