ID A0A3Q7SSU0_VULVU Unreviewed; 728 AA.
AC A0A3Q7SSU0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Zinc finger protein 408 {ECO:0000313|RefSeq:XP_025859853.1};
GN Name=ZNF408 {ECO:0000313|RefSeq:XP_025859853.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025859853.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025859853.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025859853.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025859853.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_025859853.1; XM_026004068.1.
DR AlphaFoldDB; A0A3Q7SSU0; -.
DR STRING; 9627.ENSVVUP00000037477; -.
DR KEGG; vvp:112924084; -.
DR OrthoDB; 5348752at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd10520; PR-SET_PRDM17; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR044412; PRDM17_PR-SET.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24379:SF67; IP01257P-RELATED; 1.
DR PANTHER; PTHR24379; KRAB AND ZINC FINGER DOMAIN-CONTAINING; 1.
DR Pfam; PF21549; PRDM2_PR; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 357..384
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 385..412
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 413..440
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 441..468
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 472..499
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 500..527
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 528..555
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 555..582
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 583..610
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 611..638
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 201..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 628..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..652
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 728 AA; 80220 MW; DA3EDF15C008E2FB CRC64;
MEEAEELLSK GERLRLAPDP RLGLDLGWIP SGQGCAQGLK DFPPEPTRAV LALQSLPRGL
ALGPSFAEEQ RLGVWCVGEP LQPGLLWGPL EEESVPEQKD EGVKPRRKED VSLGPWGDVC
ACEQSSGWIS LVQRSRLESE GNVAPVRISE KLHLQVYRII LPGFELLLWP QPPSDGLSHT
QPRLEEAAMA VLTEVDSVVQ QEVDSPGEDA TEPWTDPGHQ SPPSIQAESM VGPGLKPQTQ
DQLYKETQLL GPLPQDGSMD EEDPAQTQMP PESQSSSATQ QGTESSESSS SSSARDNQLR
AYVVKKLRGP SGQCPPREMT SEPRAQHAGE QQQPGFPACL RSPPGPAGSS SKQRRRYRCG
ECGKAFLQLC HLKKHAFVHT GHKPFLCTEC GKSYSSEESF KAHMLGHRGV RPFPCPQCDK
AYGTRRDLKE HQVVHSGARP FACDQCGKAF ARRPSLRLHR KTHQVPAPPA PCPCPVCGRP
LANQGSLRNH MRLHTGEKPF LCPHCGRAFR QRGNLRGHLR LHTGERPYHC PHCADAFPQL
PELRRHLISH TGEAYLCPVC GKALRDPHTL RAHERLHSGE RPFPCPQCGR AYTLATKLRR
HLKSHLADKP YRCPTCGMGY TLPQSLKRHQ LSHQPGVPTS PPSSPPSMPP AVSEPTVVLL
QTEPELLDAC REQDVSPTQD VFEVTISESQ DKCFVVPEEP GPTSSLVFIH KDMGFSAWAE
VVEVETGT
//
