ID   A0A3Q7STF7_VULVU        Unreviewed;       431 AA.
AC   A0A3Q7STF7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Beclin-2 {ECO:0000313|RefSeq:XP_025859041.1};
GN   Name=BECN2 {ECO:0000313|RefSeq:XP_025859041.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025859041.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025859041.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025859041.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025859041.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the beclin family.
CC       {ECO:0000256|ARBA:ARBA00005965}.
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DR   RefSeq; XP_025859041.1; XM_026003256.1.
DR   AlphaFoldDB; A0A3Q7STF7; -.
DR   KEGG; vvp:112923422; -.
DR   OrthoDB; 11439at2759; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   Gene3D; 6.10.250.3110; -; 1.
DR   Gene3D; 1.10.418.40; Autophagy protein 6/Beclin 1; 1.
DR   InterPro; IPR007243; Atg6/Beclin.
DR   InterPro; IPR038274; Atg6/Beclin_C_sf.
DR   InterPro; IPR041691; Atg6/beclin_CC.
DR   InterPro; IPR040455; Atg6_BARA.
DR   PANTHER; PTHR12768; BECLIN 1; 1.
DR   PANTHER; PTHR12768:SF5; BECLIN-2; 1.
DR   Pfam; PF04111; APG6; 1.
DR   Pfam; PF17675; APG6_N; 1.
PE   3: Inferred from homology;
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT   DOMAIN          120..242
FT                   /note="Atg6/beclin coiled-coil"
FT                   /evidence="ECO:0000259|Pfam:PF17675"
FT   DOMAIN          246..426
FT                   /note="Atg6 BARA"
FT                   /evidence="ECO:0000259|Pfam:PF04111"
FT   COILED          152..242
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   431 AA;  49754 MW;  5C25E46EC21BB538 CRC64;
     MSSIRFICQG CRQPMRLSQS TGTLGLETTQ RPAASTFSSA QQEPRETLVC GPTSKVEIDS
     EKLPDASCST LPGDGKMFWD SPKNFILLGK FDPARTLSNI QNTTRDIFDI LTGEKYVDHP
     LCEDCTDKLL EVLDTQLIIV DSENENYKYW RGRICEEEMK TLQEELEGLE LEEARLVQEL
     KEVEKKQERV AEDLEAAQAE TEMLEQQDKQ YWKDYSNLKW QQLELQDELK SMERQLRHAQ
     IQWGRLKKTN VFSATFEIRY DGPVGIINSF RLGCLPTVPV SWKEINMAWG QTALLLLALS
     NKIGLEFQRY QLIPCGNRSY LKSLTNDPVE LPLFCIMRQS TCLDLKFDQA MMAFLDCMQQ
     FKEEAEKGKW GLCLPCRIHV KNGLMEDSGS TGEFYSIRTY LNTEEQWTKA LKLMLINLKC
     SLTWVSLRYQ E
//