ID   A0A3Q7SUG3_VULVU        Unreviewed;      1114 AA.
AC   A0A3Q7SUG3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Ras-associating and dilute domain-containing protein isoform X4 {ECO:0000313|RefSeq:XP_025867144.1};
GN   Name=RADIL {ECO:0000313|RefSeq:XP_025867144.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025867144.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025867144.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025867144.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025867144.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025867144.1; XM_026011359.1.
DR   AlphaFoldDB; A0A3Q7SUG3; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd15472; Myo5p-like_CBD_Rasip1; 1.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   CDD; cd17116; RA_Radil_like; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   InterPro; IPR037983; CBD_Rasip1/Radil.
DR   InterPro; IPR002710; Dilute_dom.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR16027; DILUTE DOMAIN-CONTAINING PROTEIN YPR089W; 1.
DR   PANTHER; PTHR16027:SF3; RAS-ASSOCIATING AND DILUTE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01843; DIL; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM01132; DIL; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS51126; DILUTE; 1.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS50200; RA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT   DOMAIN          61..164
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          494..760
FT                   /note="Dilute"
FT                   /evidence="ECO:0000259|PROSITE:PS51126"
FT   DOMAIN          1015..1100
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          184..234
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          810..841
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          877..1005
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..229
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1114 AA;  121756 MW;  246A0D3359557E26 CRC64;
     MFYGTHFIMS PPTKSKLKRQ SQLLSSVLSR TLSYKYRDLD TTFSSLGASD DPAELSTQLS
     APGVLKVFGD SVCTGTHYKS VLATGMSSAQ ELVKEALERY ALSPECASQY VLCDVVGQAG
     DPGQQWQAEC FRVFGDNEKP LLIQELWKPR EGLSRRFELR KRSDVEELAA KDVDTLTAGI
     NAQARRLQRS RAKGTPALAS EGAQSPPTPR LRRTVSESSL SSATTPGPEE RGQETMRYSL
     YESPHLLLLQ GYSQQHDSLV YLLNREQHTV GQRTPSSKPS VSLSAPDILP LHCTIRRHQP
     SGPEQAGSRL VLEPIPGAPV SVNFSEVGGR AVVLRHGDLL SLGLYYLLLF KDPAQAQPLP
     AQALARLRAV PRSCRMCGAS LRARGASNSG STWVPPPRPR LLHLEFEPEV EDALLQRIMT
     LIEPSGDDHK LTPAFLLCLC IQHSATRLEP GSFGQLLLKI AKAIRETVWE KTKELAEKQA
     QLQEPISLAS FSMAGLVPDL QHILFWMSNS VELLYFIQQK CPLYMQSLEE ELDVTGSKES
     LFSCTLTASE EAMAVLEEVI LYAFQQCVYY VSKSLYVCLP ALLECPPFQT ERRESWCSAP
     QLPEELRHVV SVYQATLDLL RQFQMHPEIA SQVLAYLFFF SSTLLFNQLL DKGPSLSCFH
     WPRGVQACAR LQQLLEWMRS AGYGEAGERF FRKLSCTLNL LATPRAQLIQ MSWANLRAAF
     PTLSPAQLHR LLTQYQLASA MGPMSAWEPG AQDSPDAFKS EDVLESYENP PPIVLPSEGF
     QVDLEADCLD DSIYQHLLYI RHFLWSLRSK PSPGGGPSQP EYLQVPGSDT GPGCCPGQLV
     EPRLQKAGDT PLVLPPRWAP PVSPSIPELF LPLPCLQGPH HTTPEGHPEG QSCPLVSRGA
     REASQMRALP SSGAPRAQGP PGRQSRGGPQ AGPLHADSSC LLTPPGTPLS LEPAVPDWPE
     PGGTCGQALL EGRKNGQSGS RGAAPEGDGA GHEDESPAAP SSHSSSTEDF CYVFVVELER
     GPSGLGMGLI DGMHTPLGSP GLYIQTLLPG SPAASDGRLS LGDRILEVNG SSLMGVSYLR
     AVDLIRHGGK KMRFLVAKSD VETAKKIRFR TPPP
//