ID   A0A3Q7SWW0_VULVU        Unreviewed;       696 AA.
AC   A0A3Q7SWW0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Protein shisa-6 {ECO:0000313|RefSeq:XP_025861473.1};
GN   Name=SHISA6 {ECO:0000313|RefSeq:XP_025861473.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025861473.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025861473.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025861473.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025861473.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025861473.1; XM_026005688.1.
DR   AlphaFoldDB; A0A3Q7SWW0; -.
DR   STRING; 9627.ENSVVUP00000042006; -.
DR   KEGG; vvp:112925002; -.
DR   OrthoDB; 4086546at2759; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026910; Shisa.
DR   PANTHER; PTHR31774:SF0; PROTEIN SHISA-6; 1.
DR   PANTHER; PTHR31774; PROTEIN SHISA-9-RELATED; 1.
DR   Pfam; PF13908; Shisa; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        321..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          386..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          545..574
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          641..667
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        386..406
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        641..666
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   696 AA;  78249 MW;  E46B20B9A786D117 CRC64;
     MHRGKEKVVT MEEEMALQHV HCQCRDEPAL LTMLAISANG HRLPKIYLSL LSDFTWIIRR
     AFRLLFSHAI FLTSVDSEIQ RMCKSDRGFP LSGTHQELSI NCRINSSSLA GDTMPFCQLS
     LEDSLGIYAQ LLNLCSHPLP VRSLTPVLSE HSEPIFTWDM AMDLENICLC LRSALQTSLL
     DGGELAYSSF TRHLSQCLVE CRLSTPVYLT EALRVAAAAA AAAVAAVAAA SAAVTYETCW
     GYYDVSGQYD KEFECNNSES GYLYCCGTCY YRFCCKKRHE KLDQRQCTNY QSPVWVQTPS
     TKVVSPGPEN KYDPEKDRTN FTVYITCGVI AFVIVAGVFA KVSYDKAHRP PREMNIHRAL
     ADILRQQGPI PIAHCERETI SAINTSPKEN TPVRSSSKNH YTPVRTAKQT PGHYGKDAYR
     SGGPDLHNFI SSGFVTLGRG HTKGDHQYNH PILSSAAQTP THEKPRMNNI LTSATEPYDL
     SFSRSFQNLA HLPPSYESAV KTHPSKYSSL KRLTDKEADE YYMRRRHLPD LAARGTLPLN
     VIQMSQQKPL PRERPRRPIR AMSQDRVLSP ERGLPDDFGL PYDRILSDEQ LLSTERLHSQ
     DPLLSPERTA FPEQSLSRAI SHTDVFVSTP VLDRYRMTKM HSHPSASNNS YATLGKSQTA
     AKRQAFASRR HNTVEQLHYI PGHHTCYTAS KTEVTV
//