ID A0A3Q7SWY5_VULVU Unreviewed; 349 AA.
AC A0A3Q7SWY5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DNA repair protein XRCC3 {ECO:0000313|RefSeq:XP_025868454.1, ECO:0000313|RefSeq:XP_025868455.1};
GN Name=XRCC3 {ECO:0000313|RefSeq:XP_025868454.1,
GN ECO:0000313|RefSeq:XP_025868455.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025868454.1};
RN [1]
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025868455.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025868455.1};
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025868454.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025868454.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025868454.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025868454.1; XM_026012669.1.
DR RefSeq; XP_025868455.1; XM_026012670.1.
DR STRING; 9627.ENSVVUP00000001224; -.
DR Ensembl; ENSVVUT00000001826; ENSVVUP00000001224; ENSVVUG00000000935.
DR KEGG; vvp:112930297; -.
DR OMA; PCLGLQW; -.
DR OrthoDB; 3177495at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0033065; C:Rad51C-XRCC3 complex; IEA:Ensembl.
DR GO; GO:0005657; C:replication fork; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0008821; F:crossover junction DNA endonuclease activity; IEA:Ensembl.
DR GO; GO:0000400; F:four-way junction DNA binding; IEA:Ensembl.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR GO; GO:0036297; P:interstrand cross-link repair; IEA:Ensembl.
DR GO; GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IEA:Ensembl.
DR GO; GO:0010824; P:regulation of centrosome duplication; IEA:Ensembl.
DR GO; GO:0071140; P:resolution of mitotic recombination intermediates; IEA:Ensembl.
DR GO; GO:0090656; P:t-circle formation; IEA:Ensembl.
DR GO; GO:0000722; P:telomere maintenance via recombination; IEA:Ensembl.
DR CDD; cd19491; XRCC3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR047348; XRCC3-like_C.
DR PANTHER; PTHR46487; DNA REPAIR PROTEIN XRCC3; 1.
DR PANTHER; PTHR46487:SF1; DNA REPAIR PROTEIN XRCC3; 1.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF005856; Rad51; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT DOMAIN 78..259
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
SQ SEQUENCE 349 AA; 37953 MW; E31F36622B35F315 CRC64;
MDLDQLDLNP RIIAAVKKAK LKSIKEVLHF SGPDLQRLTS LSSLDVQHLL RAASSRLRGG
GVLTALQLCE REGGLPARPR RLSLGCPVLD RLLRGGLPLD GVTELAGLSS AGKTQLALQL
CLTVQFPPCH GGLDAGAMYI CTEDVFPNLR LQQLIAQQRR LRTDVPGEVV SRIKFSNQIF
IEHVADVDSL LECVREKVPV LLSRGMARLV VIDSVAAPFR CEFDGPALVP RARHLQALGA
ALRRLSCAFQ SPVLCINQVT EATEEQGTAP RPHGLWDERV SPALGMTWSN QLLMRLMVHR
RRPGDKAVTP AGPPDRTLSV VFAPHLPPSS CSYTVNAEGV RGTPGTESY
//
