ID A0A3Q7SY27_VULVU Unreviewed; 260 AA.
AC A0A3Q7SY27;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Tumor necrosis factor receptor superfamily member 9 isoform X1 {ECO:0000313|RefSeq:XP_025860871.1, ECO:0000313|RefSeq:XP_025860872.1};
GN Name=TNFRSF9 {ECO:0000313|RefSeq:XP_025860871.1,
GN ECO:0000313|RefSeq:XP_025860872.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025860871.1};
RN [1]
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025860872.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025860872.1};
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025860871.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025860871.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025860871.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR RefSeq; XP_025860871.1; XM_026005086.1.
DR RefSeq; XP_025860872.1; XM_026005087.1.
DR KEGG; vvp:112924681; -.
DR OrthoDB; 5471029at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:InterPro.
DR CDD; cd13410; TNFRSF9; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR020413; TNFR_9.
DR InterPro; IPR034020; TNFRSF9_N.
DR PANTHER; PTHR47139; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9; 1.
DR PANTHER; PTHR47139:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9; 1.
DR Pfam; PF00020; TNFR_c6; 2.
DR PRINTS; PR01924; TNFACTORR9.
DR SMART; SM00208; TNFR; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_025860871.1,
KW ECO:0000313|RefSeq:XP_025860872.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 192..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 52..91
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 52..91
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DISULFID 70..83
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 73..91
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 260 AA; 28343 MW; 28C043AD80CC9523 CRC64;
MQDFTMGSGY YNIVATVLLV MNFERTRSMQ DSCSKCPAGT FCGKSKSQIC IPCPPNSFSS
TSGQKACDIC RQCEGVFRTK KVCSPISNAE CECISGFHCL GAGCTMCEQD CKQGQELTKQ
GCKDCRFGTF NDQKHGICQP WTNCSLDGKS VLVNGTKESD AVCGPASAGF SPGTASATTP
APARDPGHTS QIIIFFLALM SVAVLFLVFF LILHFSVIKH GRKKLLYLFK QPFMRPVQTA
QEEDACSCRF PEEEEGECDL
//
