ID A0A3Q7T8G5_VULVU Unreviewed; 370 AA.
AC A0A3Q7T8G5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Leucine-rich repeat and transmembrane domain-containing protein 2 {ECO:0000313|RefSeq:XP_025851264.1, ECO:0000313|RefSeq:XP_025851265.1};
GN Name=LRTM2 {ECO:0000313|RefSeq:XP_025851264.1,
GN ECO:0000313|RefSeq:XP_025851265.1, ECO:0000313|RefSeq:XP_025851266.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025851265.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025851264.1, ECO:0000313|RefSeq:XP_025851265.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025851264.1,
RC ECO:0000313|RefSeq:XP_025851265.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025851264.1,
RC ECO:0000313|RefSeq:XP_025851265.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025851264.1; XM_025995479.1.
DR RefSeq; XP_025851265.1; XM_025995480.1.
DR RefSeq; XP_025851266.1; XM_025995481.1.
DR STRING; 9627.ENSVVUP00000028034; -.
DR Ensembl; ENSVVUT00000037217; ENSVVUP00000028034; ENSVVUG00000020526.
DR KEGG; vvp:112917423; -.
DR OMA; QISWIAC; -.
DR OrthoDB; 4193933at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF175; LEUCINE RICH REPEATS AND TRANSMEMBRANE DOMAINS 2; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|RefSeq:XP_025851264.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 307..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..72
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 198..251
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 261..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..288
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 370 AA; 41281 MW; A2288AFC14009EA8 CRC64;
MLARGSSPEQ RTRLALQWRQ ISWIACWITL YAVEALPACP FSCKCDSRSL EVDCSGLGLT
MVPPDLPAAT RTLLLLNNKL SALPSWAFAN LSSLQRLDLS NNFLDQLPRS IFGDLTNLTE
LQLRNNSIRT LDRDLLQHSP QLRHLDLSIN GLAQLPPGLF DGLPALRSLS LRSNRLQNLD
RLTFEPLASL QLLQVGDNPW ECDCNLRDFK HWMEWFSYRG GRLDQLACTL PKELRGKDMR
VVPMEMFNYC SQLEDENSSA GLDIPGPPCT KASPEPAKPK PGAEPEPEPS TACPQKQRYR
PVSVRRAIGT VIIAGVVCGI VCIMMVVAAA YGCIYASLMA KYHRELKKRQ PLMGDPEGEH
EDQKQISSVA
//
