ID   A0A3Q7TAL5_VULVU        Unreviewed;       662 AA.
AC   A0A3Q7TAL5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=G-protein-signaling modulator 2 isoform X2 {ECO:0000313|RefSeq:XP_025852120.1};
GN   Name=GPSM2 {ECO:0000313|RefSeq:XP_025852120.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025852120.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025852120.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025852120.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025852120.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GPSM family.
CC       {ECO:0000256|ARBA:ARBA00006600}.
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DR   RefSeq; XP_025852120.1; XM_025996335.1.
DR   AlphaFoldDB; A0A3Q7TAL5; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR003109; GoLoco_motif.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45954:SF3; G-PROTEIN-SIGNALING MODULATOR 2; 1.
DR   PANTHER; PTHR45954; LD33695P; 1.
DR   Pfam; PF02188; GoLoco; 4.
DR   Pfam; PF13374; TPR_10; 1.
DR   Pfam; PF13424; TPR_12; 2.
DR   Pfam; PF13176; TPR_7; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00390; GoLoco; 4.
DR   SMART; SM00028; TPR; 7.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50877; GOLOCO; 4.
DR   PROSITE; PS50005; TPR; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          43..76
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          223..256
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   662 AA;  73915 MW;  51DF17882355E43D CRC64;
     MEASCLELAL EGERLCKSGD CRAGVSFFEA AVQVGTEDLK TLSAIYSQLG NAYFYLHDYA
     KALEYHHHDL TLARTIGDQL GEAKASGNLG NTLKVLGNFD EAVVCCQRHL DISRELNDKV
     GEARALYNLG NVYHAKGKSF GCPGPQDIGE FPEEVRNALQ AAVDYYEENL SLVTALGDRA
     AQGRAFGNLG NTHYLLGNFR DAVIAHEQRL LIAKEFGDKA AERRAYSNLG NAYIFLGEFE
     TASEYYKKTL LLARQLKDRA VEAQSCYSLG NTYTLLQDYE KAIDYHLKHL AIAQELNDRI
     GEGRACWSLG NAYTALGNHD QAMHFAEKHL EISREVGDRS GELTARLNLS DLQMVLGLSY
     STNNSIMSEN IEIDNSLHGA RPKFGRRHSM ENMELMKLTP EKVQNWNSEI LAKQKPLIAK
     PSAKLLFVNR LKGKKCKTNS STKVLQDASN SIDRRIPNSQ RKVSTDTIGD EGFFDLVSRF
     QSNRMDDQRC CLQEQSCGPA STAASSTPPR VMLKTPSVSM VSPNTDEFLD LLASSQSRRL
     DDQRASFSNL PGLRLTQNNN KSVLGHLMTN DNKEPDEDFF DILVKCQGSR LDDQRCAPPP
     ATTKGPTVPD EDFFSLILRS QAKRMDEQRV LLQRDQNRDT EFGLKDLFQS KALLEFKNTG
     KK
//