ID A0A3Q7TDX7_VULVU Unreviewed; 353 AA.
AC A0A3Q7TDX7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=WNT7B {ECO:0000313|RefSeq:XP_025875564.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025875564.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025875564.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025875564.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025875564.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR RefSeq; XP_025875564.1; XM_026019779.1.
DR AlphaFoldDB; A0A3Q7TDX7; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR GO; GO:0009888; P:tissue development; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19350; wnt_Wnt7b; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR013300; Wnt7.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF73; PROTEIN WNT-7B; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01891; WNT7PROTEIN.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 353 AA; 39377 MW; B5AE7C7F63F7DFDF CRC64;
MLLLSPRGAL LSVYCPQIFL ILSSGSYLAL SSVVALGANI ICNKIPGLAP RQRAICQSRP
DAIIVIGEGA QMGINECQYQ FRFGRWNCSA LGEKTVFGQE LRVGSREAAF TYAITAAGVA
HAVTAACSQG NLSNCGCDRE KQGYYNQAEG WKWGGCSADV RYGIDFSRRF VDAREIKKNA
RRLMNLHNNE AGRKVLEERM KLECKCHGVS GSCTTKTCWT TLPKFREVGH MLKEKYNAAV
QVEVVRASRL RQPTFLRIKQ LRSYQKPMET DLVYIEKSPN YCEEDAATGS VGTQGRLCNR
TSPGADGCDT MCCGRGYNTH QYTKVWQCNC KFHWCCFVKC NTCSERTEVF TCK
//
