ID   A0A3Q7THI3_VULVU        Unreviewed;       692 AA.
AC   A0A3Q7THI3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Band 4.1-like protein 2 isoform X11 {ECO:0000313|RefSeq:XP_025869168.1};
GN   Name=EPB41L2 {ECO:0000313|RefSeq:XP_025869168.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025869168.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025869168.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025869168.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025869168.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025869168.1; XM_026013383.1.
DR   AlphaFoldDB; A0A3Q7THI3; -.
DR   Proteomes; UP000286640; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   CDD; cd13184; FERM_C_4_1_family; 1.
DR   CDD; cd17202; FERM_F1_EPB41L2; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR008379; Band_4.1_C.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR000798; Ez/rad/moesin-like.
DR   InterPro; IPR014847; FA.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR   PANTHER; PTHR23280:SF17; BAND 4.1-LIKE PROTEIN 2; 1.
DR   Pfam; PF05902; 4_1_CTD; 1.
DR   Pfam; PF08736; FA; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   PIRSF; PIRSF002304; Membrane_skeletal_4_1; 2.
DR   PRINTS; PR00935; BAND41.
DR   PRINTS; PR00661; ERMFAMILY.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM01195; FA; 1.
DR   SMART; SM01196; FERM_C; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS00660; FERM_1; 1.
DR   PROSITE; PS00661; FERM_2; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT   DOMAIN          206..487
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
FT   REGION          1..186
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..53
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..124
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..186
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   692 AA;  76577 MW;  C1C41D922D1FA08C CRC64;
     MTTEVGPAAE VKQEPEKVGA AAMERPKEAA ENWQNPPSEP EEPGPPAPPA ADSPGRPRQK
     REGEPSESRG LARFLPPWLK KQKSYTLVVA GDKEPKEPPR AVVEQVAGRE ESPPEGERPP
     QAEAQEHAGS RQQEVTAGVK DEKPEKPGAS PEAQSAEEVG KGKEKVDEVQ EDASEEAAKR
     ESKEVQTNEL KAEKAAQKAA KKTKMVQCKV MLLDGTEYSC DLEKRAKGQV LFDKVCEHLN
     LLEKDYFGLL FQESPEQKNW LDPAKEIKRQ LRNLPWLFTF NVKFYPPDPS QLTEDLTRYL
     LCLQLRQDIA SGRLPCSFVT HALLGSYTLQ AELGDHDPEE HGGSDLSDFQ FAPMQTKELE
     EKVAELHRTH RGLSPAQADS QFLENAKRLS MYGVDLHHAK DSEGVDIKLG VCANGLLIYK
     DRLRINRFAW PKILKISYKR SNFYIKVRPA ELEQFESTIG FKLPNHRAAK RLWKVCVEHH
     TFYRLVSPEQ PPKAKFLTLG SKFRYSGRTQ AQTRQASTLI DRPAPHFERT SSKRVSRSLD
     GAPLGVVEPG LVKDLPSAAG ELPAGPGVDS TAAVQDGDGT RDLRSPAKAP HVQFVEGKID
     GGAGGDSGTL LTAQTITSES VSTTTTTHIT KTVKGGISET RIEKRIVITG DADIDHDQAL
     AQAIREAREQ HPDMSVTRVV VHKETELDEG EE
//