ID A0A3Q7TJX1_VULVU Unreviewed; 432 AA.
AC A0A3Q7TJX1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Tubulin epsilon chain isoform X3 {ECO:0000313|RefSeq:XP_025861606.1, ECO:0000313|RefSeq:XP_025861607.1};
GN Name=TUBE1 {ECO:0000313|RefSeq:XP_025861606.1,
GN ECO:0000313|RefSeq:XP_025861607.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025861607.1};
RN [1]
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025861606.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025861606.1};
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025861607.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025861607.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025861607.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the tubulin family.
CC {ECO:0000256|ARBA:ARBA00009636, ECO:0000256|RuleBase:RU000352}.
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DR RefSeq; XP_025861606.1; XM_026005821.1.
DR RefSeq; XP_025861607.1; XM_026005822.1.
DR Ensembl; ENSVVUT00000011861; ENSVVUP00000009006; ENSVVUG00000006727.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR CDD; cd02190; epsilon_tubulin; 1.
DR Gene3D; 1.10.287.600; Helix hairpin bin; 1.
DR Gene3D; 3.40.50.1440; Tubulin/FtsZ, GTPase domain; 1.
DR InterPro; IPR004057; Epsilon_tubulin.
DR InterPro; IPR008280; Tub_FtsZ_C.
DR InterPro; IPR000217; Tubulin.
DR InterPro; IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
DR InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR InterPro; IPR023123; Tubulin_C.
DR InterPro; IPR017975; Tubulin_CS.
DR InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR PANTHER; PTHR11588; TUBULIN; 1.
DR PANTHER; PTHR11588:SF13; TUBULIN EPSILON CHAIN; 1.
DR Pfam; PF00091; Tubulin; 1.
DR Pfam; PF03953; Tubulin_C; 1.
DR PRINTS; PR01519; EPSLNTUBULIN.
DR PRINTS; PR01161; TUBULIN.
DR SMART; SM00864; Tubulin; 1.
DR SMART; SM00865; Tubulin_C; 1.
DR SUPFAM; SSF55307; Tubulin C-terminal domain-like; 1.
DR SUPFAM; SSF52490; Tubulin nucleotide-binding domain-like; 1.
DR PROSITE; PS00227; TUBULIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000352};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU000352};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000352};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT DOMAIN 6..234
FT /note="Tubulin/FtsZ GTPase"
FT /evidence="ECO:0000259|SMART:SM00864"
FT DOMAIN 236..371
FT /note="Tubulin/FtsZ 2-layer sandwich"
FT /evidence="ECO:0000259|SMART:SM00865"
SQ SEQUENCE 432 AA; 48069 MW; F33E651D1EBF3D49 CRC64;
MLSASPGLVV GDGGSISKGK ICSLKARAVL IDMEEGVVNE ILQGPLRDVF DSKQLITDIS
GSGNNWAVGH KVFGSLYREQ ILEKLRKSAE HCDCLQCFFI IHSMGGGTGS GLGTFLLKVL
EDEFPEVYRF VTSVYPSAED DVITSPYNSI LAMKELNEHA DCVLPIDNQS LFDIISKIDL
MVNSGKLGTT IKAKSLVTSS AGAVKKRHQK PFDAMNNIVA NLLLNLTSSA RFEGSLNMDL
NEISMNLVPF PQLHYLVSSL TPLYTLADVN IPTRRLDQMF SDAFSKDHQL IRADPKHSLY
LACALMVRGN VQVSDLRRNI ERLKPSLRFI SWNQEGWKTS LCSVPPVGHS HSLLALANNT
CVKPTFMELR DRFTRLYKKK AHLHHYLQIE GMEESCFMEA VSSLSRLIEE YNQLDATKSM
PVEDLPRLSI AM
//
