ID A0A3Q7TMM9_VULVU Unreviewed; 604 AA.
AC A0A3Q7TMM9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Baculoviral IAP repeat-containing protein 3 {ECO:0000313|RefSeq:XP_025862532.1, ECO:0000313|RefSeq:XP_025862534.1};
GN Name=BIRC3 {ECO:0000313|RefSeq:XP_025862532.1,
GN ECO:0000313|RefSeq:XP_025862534.1, ECO:0000313|RefSeq:XP_025862535.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025862532.1};
RN [1]
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025862534.1,
RC ECO:0000313|RefSeq:XP_025862535.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025862534.1,
RC ECO:0000313|RefSeq:XP_025862535.1};
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025862532.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025862532.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025862532.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the IAP family. {ECO:0000256|ARBA:ARBA00006672}.
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DR RefSeq; XP_025862532.1; XM_026006747.1.
DR RefSeq; XP_025862534.1; XM_026006749.1.
DR RefSeq; XP_025862535.1; XM_026006750.1.
DR STRING; 9627.ENSVVUP00000014441; -.
DR Ensembl; ENSVVUT00000018919; ENSVVUP00000014441; ENSVVUG00000010573.
DR KEGG; vvp:112925935; -.
DR OMA; CVIPILN; -.
DR OrthoDB; 383715at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:Ensembl.
DR GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0060544; P:regulation of necroptotic process; IEA:Ensembl.
DR CDD; cd00022; BIR; 3.
DR CDD; cd16713; RING-HC_BIRC2_3_7; 1.
DR CDD; cd14394; UBA_BIRC2_3; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR001370; BIR_rpt.
DR InterPro; IPR048875; BIRC2-3-like_UBA.
DR InterPro; IPR041933; BIRC2/BIRC3_UBA.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR10044:SF178; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR Pfam; PF00653; BIR; 3.
DR Pfam; PF21290; BIRC2-3-like_UBA; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00238; BIR; 3.
DR SMART; SM00114; CARD; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 3.
DR PROSITE; PS01282; BIR_REPEAT_1; 2.
DR PROSITE; PS50143; BIR_REPEAT_2; 3.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 439..529
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 557..592
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 106..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 413..440
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 604 AA; 67940 MW; 7B57C329180E31FC CRC64;
MNIVQNSIFL SNLLRSSPVF ELKYDHSCEL YRMSTYSTFP AGVPVSERSL ARAGFYYTGA
KDRVRCFCCG LMLDNWKAGD SPTGKHRNLY PSCSFIQNLS AVSTVGAASQ PPAPSSEARS
THAQSPGLER SSYFSASYTS FPVDPVDFRP SPAMSPWRAG PSCVTMKSEE DRLCTFQGWP
LAFPLPSALA RAGFYYVGPG DRVACFACGG KLSNWEPDDD ALSEHLRHFP DCPFVEGQPQ
ATVRYTASNL SMQTLAARSR TFCNWPPRAP VHPEQLASAG FYYMGHSDDV KCFCCDGGLR
CWESGDDPWV EHAKWFPRCE YLIRIKGQEF ISQIQASYPH LLEQLLSTSD NTEDENTESP
IVHFGPGEYH SEDAVMMNTP VVMAALEMGF SRSLVRQTVQ SKILSTGENY RTVNEIVSDL
LHVEDEIREE EKERAAENRE SDDVSLIRKN KMVLFQHLTY VLPILDSLLM AGVLNEQEHS
SIKQKARTSL QARELIDTVL VKGSSAVTIF KNSLQEIDPM LYKRFFVQQD RKYIPTEDIS
DLPVEEQLRR LQEERTCKVC MDKEVSIVFI PCGHLVVCRD CAPSLRRCPI CRGTVRGTVR
TFLS
//
