ID A0A3Q7TND3_VULVU Unreviewed; 549 AA.
AC A0A3Q7TND3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=WW domain-containing adapter protein with coiled-coil isoform X4 {ECO:0000313|RefSeq:XP_025856650.1};
GN Name=WAC {ECO:0000313|RefSeq:XP_025856650.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025856650.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025856650.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025856650.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025856650.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_025856650.1; XM_026000865.1.
DR AlphaFoldDB; A0A3Q7TND3; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR InterPro; IPR038867; WAC.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR15911; WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL; 1.
DR PANTHER; PTHR15911:SF6; WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT DOMAIN 141..168
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 1..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 331..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 60067 MW; 6EA1BFC0272D84D6 CRC64;
MVMYARKQQR LSDGCHDRRG DSQPYQGGDV LQALKYSSKS HPSSGDHRHE KMRDAADPSP
PNKMLRRSDS PENKYSDGTG HSKAKNVHIH RVRERDGGTS YSPQENSHNH SALHSSNSHS
SNPSNNPSKT SDTPYDSADD WSEHISSSGK KYYYNCRTEV SQWEKPKEWL EREQRQKEAN
KMAVNSFPKD RDYRREVMQA TATSGFASGK STPGDKSVSH SCTTPSTSSA SGLNPTSAPP
TSASAIPVSP VPQSPIPPLL QDPNLLRQLL PALQATLQLN NSNVDISKIN EVLTAAVTQA
SLQSIIHKFL TAGPSAFNIT SLISQAAQLS TQAQPSNQSP MSLTSDASSP RSYVSPRIST
PQTNTVPIKP LISTPPVSSQ PKVSTPVVKQ GPVSQSATQQ PVTADKQQGH EPVSPRSLQR
SNSQRSPSPG PNHTSSSNAS NATVVPQNSS ARPTCSLTPT LAAHFNENLI KHVQGWPADH
AEKQASRLRE EAHNMGSVHM SEICTELKNL RSLVRVCEIQ ATLREQRILF LRQQIKELEK
LKNQNSFMV
//
