GenomeNet

Database: UniProt
Entry: A0A3Q7TP02_VULVU
LinkDB: A0A3Q7TP02_VULVU
Original site: A0A3Q7TP02_VULVU 
ID   A0A3Q7TP02_VULVU        Unreviewed;      3062 AA.
AC   A0A3Q7TP02;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   10-FEB-2021, entry version 12.
DE   SubName: Full=centromere protein F {ECO:0000313|RefSeq:XP_025856900.1};
GN   Name=CENPF {ECO:0000313|RefSeq:XP_025856900.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025856900.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025856900.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025856900.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025856900.1};
RG   RefSeq;
RL   Submitted (OCT-2020) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_025856900.1; XM_026001115.1.
DR   Ensembl; ENSVVUT00000014884; ENSVVUP00000011370; ENSVVUG00000008374.
DR   KEGG; vvp:112921785; -.
DR   OMA; YNAQLVQ; -.
DR   Proteomes; UP000286640; Genome assembly.
DR   GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT   DOMAIN          1..308
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1845..1987
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2083..2222
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2265..2404
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2920..2964
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          201..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1313..1334
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2837..3062
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          419..439
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          464..502
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          524..616
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          624..686
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          719..760
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          840..867
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          904..958
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          963..993
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1030..1078
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1090..1110
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1132..1152
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1237..1271
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1500..1563
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1742..1804
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1842..1862
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1891..1911
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1919..1949
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1968..2037
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2059..2086
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2094..2230
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2245..2268
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2276..2303
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2311..2482
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2500..2555
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2570..2668
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2670..2777
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2785..2815
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        201..237
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        249..277
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2837..2857
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2867..2884
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2891..2905
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2906..2935
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2950..3028
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3062 AA;  351260 MW;  73F452151F4D1CAF CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKT
     EGANLKRENQ SLMEICENLE KTKQKMSHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ TAQAADVSLH SCTTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA TTKVSQAIPQ STMNHRDIAR HQASSSVFSW QQEKTPSRLS SSALKTPMRR
     DLSAAHLSGE QEVTPSRSTL QRGKRDANGS FCDNSSNSHL LDQLKAQNQE LRNKISDLEL
     HLQGQEKEMK GQVNKCHELQ LHLEKAKAEL IEKEKILNKS RDELMRTTAQ YDQASSKCTA
     LEQKLKRLSE DLSCQRQNAE SAKSSLEQKI KQKEKEFQEE LSRQQRAFQA LDQESTQMKG
     RLTQELQQAK NTHNILQADL DKVTSGKYQL EKTLEEFKQK FCRAEQALQA SQVKESELRK
     SNEEAKKEYS LLKSRSEQQA REVCHLEEEL RKAKQSLSQS QNFAEEMRAK NASQETMLRD
     LQDKINQQEN SLTLEKLKLA LADLEKQRDC SQDLLKKREH HIEQLNDKLS KLEKESEALL
     IALELKKKEY EELKEEKTLF AHWKSENEQL LRQLESEKGS LQSKVNHLET CLKTQQIKSH
     EYNEKVRTLE IESENLNVEI RNLHNVIDSK TVEVETQKQA YVDLQQKAEF SDQKHKKEME
     NMCLKISELT GQVEDLEQKL QLLSNEVIDK DHRYQDLQAE YESLQDLLKP KDSSLVTNEA
     HHRSLLAFEQ PSAMNNSFAN IIGEQGSMPS ERSKCHREAD QSPRSSAVLQ NRVTSLEFSL
     ESQKQMNSDL QKQCQELVQI RGEIEENLIK AEQMHQSFVA ETSQRISKLQ EDSSIHQNAF
     AETLVALENK EREFQLLNEK LETEQAEIQE LKKSNHLLQE SLKELQLLSE TLSSEKKEMS
     STISLNRKEI EDLAQENETL KEINATLNQE KITLLQKSES FSNCIDERDK SILELSNQYK
     EERLLLQQRC EETGRAFEDL SEKYKAAQEK NSELECLLNE CTSACENRQK ELEHLKETFA
     REHQALVTKL ALAEETNQNL VLELGAMQQD LRSEMADIHN NSKSEVDGLK QIMTLKEEQG
     NIQKELNSLI QEKEHLMMLM ETKQEHQILE SEPVSDSVKG ESEINKCHVQ LPMDLETGNL
     QQDAQSQELS SPKDCDIGTE EKYISVLHEL STSQNDNAHL QCSLQAAMSK LSELEKMCEM
     LQVEKLELMS ELNDSRSECI TATSKMTEGM EKLVNEVKIL NDESGLLQGE LEKEMAEGES
     GEQQNEQKGA SLNPLDDRNC YEHLTLSNKE VQMHFAELQE KFLSLQSEHK ILHDQHCQVS
     SKMSELQSYV DALKAENSML STSLRNFQGD LVKEEMPEPQ AGHFLSLSFS CVTDSPSLRS
     LGESSFCKDL LDQTGETSLL NNLDGTIAAN QSNIEEGSCC SPEEESLTKR EILSAPGRSV
     EDLETQCQMY LQSLKKLEDK IESQEILKNK EIKELEQLLS SEREELDSLR KQYLSENEQW
     QQKLTSVTME MESKLAAEKK QTEHLSFELE VARLQLQGLD LSSRSLLGTD LEDALRGGNT
     SCDVKESEEY TLETKERTPK RDTHQICEEG VQQDLNLEME KITKTSPVRF TGEWSSKQSP
     ETSYETLVQD KTQGCLDISE LSLSGPNALV PIDFLETQVT IENLQLQVKE SSNENLRLLH
     VIEERDKKIE SLLDEIRELD SKLVLQEARI TTKMEACVEL EKIVEELKKE KSNLSERLES
     SFHDNQELHQ RTESLEGLSS HLEIGADKLS HAVIEDNVAK VNDNWRERFL DVENELKRIK
     SEKGSIEHHA LSVEAELETV QTEKLYLVKD NENKQKAITC LEEELSVVTS ERNQLHGQLD
     TLSKEKKELD LMSEKMKQKI QELESREDEC LHPSDMAGAE VKDKMQLVQR LSSDVTQLLE
     DNTRLQEQLQ SLEKDSQALS LVKSELEIQI EQLNKEKESL SRESESLQAR LHESEHEKLT
     VAKALEGALM EKGEVAVRLS STQEEVHQLR KGIEKLRIRI EADEKKQLHV LEKLRESERK
     ADALQDKVEN LERELQMSEE NQELVILDAE NSKAEVETLK TQMELTTKSL KDLESDLVTV
     RFEKENLIKQ LQDKQGQVSE LDTLVSSFKG LLEEKEREKI EMKEESRAAL ELLRTQLKEL
     NEEIAALCHD QEIQKVKEQS LDPLVQEIHQ LRNNTEKLKA RLEADEKEQL QVLGKLKETE
     HQANFLKDRV ESLERELEIS GKNQECVVLE AENSKAEVGT LKVKIEEMAQ NLRDLELDLV
     HIRSEKENAI KELQKEQERV SELETLNSSL ENLLQEKEQE KVQMSEESKT AVEMLQTQLK
     ELNEEMAALC HDQDTWKAQE QNLRSQVDAL EHEKAQLLQG LDEAKNNYIN VQSSANSLHQ
     QVEDDKQKLK KKDEEISMLK SQIHDREQLA SKLSQVEGEQ QLWKKQKVEL ENLMVELEQK
     IQVLQSKNDT LQATLEALQK SHKDLEKELE LTKMENVSFI EKVNTMTGKE TELQREMHEM
     AQKTSELKEE FTGEKNRLTE QLNTMSEEIN SSRGQLKELM LENSELKNSL DCIHKDQLEK
     EEKVREEIAN YQLQLQEAEK KHQALLLDTN KQYEMEIQTY QEKLSSKEEC LSSQKAEIDL
     LKSSKEELNN SLKATTQLLE ELKKTKADHV KYTNQLKKEN ERAQGKIKLL IKSCKQLEEE
     KEMLQKELSH LEATQENQKT GTVVDSNAEE LMAEMKELKE TLEEKTKEAD EYLDKYCSLL
     ISHEKLEKAK EMLETQVTRL SSRSKPHLQN SPLLNSVVPE ESLAPSATEK KLSSGQNTSS
     GKRQRSTGIR EDGGGTASST PETFSKKSRK AVKSGIHPAE EAKDTEFEPE GLPEVVKKGF
     ADIPTGKTSP YVLRRTTMPT RTSPRLAAQK LAQSPLSLNK ENHAETSQPT AGGSRSQKVK
     VAQQSPADSS AAFREPTTRV SNLPERSSAD SPREGLRAKR SRLAPSPEAV PESKSSENCR
     VQ
//
DBGET integrated database retrieval system