ID A0A3Q7TPX0_VULVU Unreviewed; 317 AA.
AC A0A3Q7TPX0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Endophilin-A1 {ECO:0000313|RefSeq:XP_025857230.1};
GN Name=SH3GL2 {ECO:0000313|RefSeq:XP_025857230.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025857230.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025857230.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025857230.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025857230.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the endophilin family.
CC {ECO:0000256|ARBA:ARBA00006697}.
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DR RefSeq; XP_025857230.1; XM_026001445.1.
DR AlphaFoldDB; A0A3Q7TPX0; -.
DR SMR; A0A3Q7TPX0; -.
DR STRING; 9627.ENSVVUP00000000452; -.
DR Ensembl; ENSVVUT00000000709; ENSVVUP00000000433; ENSVVUG00000000404.
DR KEGG; vvp:112922000; -.
DR OrthoDB; 25371at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07613; BAR_Endophilin_A1; 1.
DR CDD; cd11803; SH3_Endophilin_A; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035824; Endophilin_A_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF50; ENDOPHILIN-A1; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR PRINTS; PR01887; SPECTRNALPHA.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..214
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 255..314
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 211..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 317 AA; 36110 MW; 5DFA79C264C85F8A CRC64;
MERKVDVTSR AVMEIMTKTI EYLQPNPASR AKLSMINTMS KIRGQEKGPG YPQAEALLAE
AMLKFGRELG DDCNFGPALG EVGEAMRELS EVKDSLDMEV KQNFIDPLQN LHDKDLREIQ
HHLKKLEGRR LDFDYKKKRQ GKIPDEELRQ ALEKFDESKE IAESSMFNLL EMDIEQVSQL
SALVQAQLEY HKQAVQILQQ VTVRLEERIR QASSQPRREY QPKPRMSLEF TTGDSTQPNG
GLSHTGTPKP AGAPMDQPCC RALYDFEPEN EGELGFKEGD IITLTNQIDE NWYEGMLHGQ
SGFFPINYVE ILVALPH
//
