ID A0A3Q7TTW0_VULVU Unreviewed; 572 AA.
AC A0A3Q7TTW0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Actin-binding LIM protein 3 isoform X4 {ECO:0000313|RefSeq:XP_025864702.1};
GN Name=ABLIM3 {ECO:0000313|RefSeq:XP_025864702.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025864702.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025864702.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025864702.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025864702.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_025864702.1; XM_026008917.1.
DR AlphaFoldDB; A0A3Q7TTW0; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR CDD; cd09329; LIM3_abLIM; 1.
DR CDD; cd09330; LIM4_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 2.
DR Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR InterPro; IPR032402; AbLIM_anchor.
DR InterPro; IPR003128; Villin_headpiece.
DR InterPro; IPR036886; Villin_headpiece_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF0; ACTIN-BINDING LIM PROTEIN 3; 1.
DR Pfam; PF16182; AbLIM_anchor; 2.
DR Pfam; PF00412; LIM; 2.
DR Pfam; PF02209; VHP; 1.
DR SMART; SM00132; LIM; 2.
DR SMART; SM00153; VHP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 4.
DR SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR PROSITE; PS51089; HP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 149..208
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 504..572
FT /note="HP"
FT /evidence="ECO:0000259|PROSITE:PS51089"
FT REGION 310..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 63831 MW; 0316BB90C8072C99 CRC64;
MSSSATDVET PAKGKWFVST TTTSTSDASP VKCVAVAWPS RASSSRTRST SALRTTSSSM
APAVTAAGTS SLARSSLRWA APTTRSASYA ACAGGQVGQR RGVELLFHLP CRKPFPIGDK
VTFSGKECVC QTCSQSMTSS KPIKIRGPSH CAGCKEEIKH GQSLLALDKQ WHVSCFKCQT
CSVILTGEYI SKDGVPYCES DYHSQFGIKC ETCDRYISGR VLEAGGKHYH PTCARCVRCH
QMFTEGEEMY LTGSEVWHPI CKQAARAEKK LKHRRTSETS ISPPGSSIGS PNRVICDIYE
NLDLRQRRAS SPGYIDSPTY SRQGMSPTFS RSPHHYYRSG DLSTATKSKT SEDISQASKY
SPAYSPDPYY AAESEYWTYH GSPKVPRARR FSSGGEEDDF DRSMHKLQSG IGRLILKEEM
KARSSSYADP WTPPRSSTSS REALHTAGYD MSLNGSPRSH YLADSDPLIS KSASLPAYRR
NGLHRTPSAD LFHYDSMNAV NWGMREYKIY PYELLLVTTR GRNRLPKDVD RTRLERHLSQ
EEFYQVFGMT ISEFDRLALW KRNELKKQAR LF
//
