ID   A0A3Q7TXT1_VULVU        Unreviewed;       349 AA.
AC   A0A3Q7TXT1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Bardet-Biedl syndrome 4 protein isoform X2 {ECO:0000313|RefSeq:XP_025874578.1, ECO:0000313|RefSeq:XP_025874654.1};
GN   Name=BBS4 {ECO:0000313|RefSeq:XP_025874578.1,
GN   ECO:0000313|RefSeq:XP_025874654.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025874578.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025874578.1, ECO:0000313|RefSeq:XP_025874654.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025874578.1,
RC   ECO:0000313|RefSeq:XP_025874654.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025874578.1,
RC   ECO:0000313|RefSeq:XP_025874654.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC       {ECO:0000256|ARBA:ARBA00004309}.
CC   -!- SIMILARITY: Belongs to the BBS4 family.
CC       {ECO:0000256|ARBA:ARBA00023778}.
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DR   RefSeq; XP_025874578.1; XM_026018793.1.
DR   RefSeq; XP_025874654.1; XM_026018869.1.
DR   Proteomes; UP000286640; Unplaced.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR44186; -; 1.
DR   PANTHER; PTHR44186:SF1; BARDET-BIEDL SYNDROME 4 PROTEIN; 1.
DR   Pfam; PF13414; TPR_11; 1.
DR   Pfam; PF13432; TPR_16; 1.
DR   Pfam; PF13181; TPR_8; 2.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF81901; HCP-like; 1.
DR   PROSITE; PS50005; TPR; 3.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   3: Inferred from homology;
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Cilium {ECO:0000256|ARBA:ARBA00023069};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          1..29
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          30..63
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          132..165
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          269..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        278..300
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   349 AA;  38231 MW;  A35DA0D6D6C74333 CRC64;
     MLGKIHLLQG DLDKAIEIYK KAVEFSPENT ELLTTLGLLY LQLGIYQKAF EHLGNALTYD
     PTNYKAILAA GSMMQTHGDF DVALTKYRVV ACAVPESPPL WNNIGMCFFG KKKYVAAISC
     LKRANYLAPF DWKILYNLGL VHLTMQQYAS AFHFVSAAIN LQPKMGELFM LLAVALTNLE
     DPENARRAYA EAARLDRCNP LVNLNYAVLL YNQGERKGAL AQFQEMEKKV RLLKDSPSLE
     FDAEMVEMAQ KLGAALQVGE ALVWTKPVKD TKSKHRSASA SKAASLQQPL GSNQALGQAM
     SSAAAYRKLP SGAGGTAQPI KPPSLPLEPE PATGAQPTEA PAQIRETQE
//