ID A0A3Q7TYT8_VULVU Unreviewed; 791 AA.
AC A0A3Q7TYT8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 2 {ECO:0000313|RefSeq:XP_025870461.1};
GN Name=NFATC2 {ECO:0000313|RefSeq:XP_025870461.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025870461.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025870461.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025870461.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025870461.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025870461.1; XM_026014676.1.
DR STRING; 9627.ENSVVUP00000031026; -.
DR KEGG; vvp:112931886; -.
DR OrthoDB; 5405363at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01178; IPT_NFAT; 1.
DR CDD; cd07881; RHD-n_NFAT; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR008366; NFAT.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR12533; NFAT; 1.
DR PANTHER; PTHR12533:SF4; NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR PRINTS; PR01789; NUCFACTORATC.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT DOMAIN 262..444
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 66..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 663..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 708..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..748
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 791 AA; 86027 MW; 36D63E7212995B7D CRC64;
MQAGGPLRGR DTGLLGEQPA LAGVAGSPRF TLPVPGFEGY REPLCLSPAS SGSSASFISD
TFSPYTSPCV SPNNGGPDDL CPQFQNIPAH YSPRTSPIMS PRTSLAEDSC LGRHSPVPRP
ASRSSSPGAK RRHSCAGALA APLPGASPQR SRSPSPQPRD DGAPAGXXXX XXXXXXXXXX
XXXXXXXXXX KMWKTSPDPS PVSAAPPKAG LPRHIYPAVE FLGPCEQEEG RSSAPESILL
VPPTWPKQLV PAIPICSIPV TASLPPLEWP LSHQSGSYEL RIEVQPKPHH RAHYETEGSR
GAVKAPTGGH PVVQLHGYME NKPLGLQIFI GTADERILKP HAFYQVHRIT GKTVTTTSYE
KIVGNTKVLE IPLEPKNNMR ATIDCAGILK LRNADIELRK GETDIGRKNT RVRLVFRVHI
PESSGRIVSL QTASNPIECS QRSAHELPMV ERQDIDSCLV YGGQQMILTG QNFTAESKVV
FTEKTTDGQQ IWEMEATVDK DKSQPNMLFV EIPEYRNKHI RASVKVNFYV INGKRKRSQP
QHFTYHPVPA IKTEPTDEYD PTLICSPAHG GLGSQPYYPQ HPMVAESPSC LVATMAPCQQ
FRSGLSSPDA RYQQQNPAAV LYQRSKSLSP SLLGYQQPAL MATPLSLADA HRSVLVHAGS
QGQGSTLLHS SPTNQQASPV IHYSPTNQPL RCGGHQEFQH IMYCENFAPG TARPGPPPVS
QGQRLSPGSY PTVIQQQNAT SQRAAKNGPP VSDQKEVLPA GVTIKQEQNL DQTYLDDELI
DTHLSWIQNI L
//
