ID A0A3Q7U9X1_VULVU Unreviewed; 545 AA.
AC A0A3Q7U9X1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein L-like isoform X1 {ECO:0000313|RefSeq:XP_025874721.1};
GN Name=HNRNPLL {ECO:0000313|RefSeq:XP_025874721.1};
OS Vulpes vulpes (Red fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025874721.1};
RN [1]
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (JAN-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_025874721.1}
RP IDENTIFICATION.
RC STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025874721.1};
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_025874721.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_025874721.1; XM_026018936.1.
DR AlphaFoldDB; A0A3Q7U9X1; -.
DR STRING; 9627.ENSVVUP00000025594; -.
DR Ensembl; ENSVVUT00000033912; ENSVVUP00000025594; ENSVVUG00000018784.
DR KEGG; vvp:112935276; -.
DR OrthoDB; 4825346at2759; -.
DR Proteomes; UP000286640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0045202; C:synapse; IEA:Ensembl.
DR GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0033120; P:positive regulation of RNA splicing; IEA:Ensembl.
DR CDD; cd12781; RRM1_hnRPLL; 1.
DR CDD; cd12786; RRM2_hnRPLL; 1.
DR CDD; cd12700; RRM3_hnRPLL; 1.
DR CDD; cd12705; RRM4_hnRPLL; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR034985; hnRPLL_RRM1.
DR InterPro; IPR034986; hnRPLL_RRM2.
DR InterPro; IPR034983; hnRPLL_RRM3.
DR InterPro; IPR034987; hnRPLL_RRM4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592:SF13; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF13893; RRM_5; 1.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000286640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000313|RefSeq:XP_025874721.1};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 79..153
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 338..412
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 60268 MW; B030622951B54A28 CRC64;
MSSSSSSPRE TYEEDREYES QAKRLKTEEG EIDYSAEEGE NRREATPRGG GDGGGGGGAG
RSFSQPEAGG SHHKVSVSPV VHVRGLCESV VEADLVEALE KFGTICYVMM MPFKRQALVE
FENIDSAKEC VTFAADEPVY IAGQQAFFNY STSKRITRPG NTDDPSGGNK VLLLSIQNPL
YPITVDVLYT VCNPVGKVQR IVIFKRNGIQ AMVEFESVLC AQKAKAALNG ADIYAGCCTL
KIEYARPTRL NVIRNDNDSW DYTKPYLGRR DRGKGRQRQA ILGEHPSSFR HDGYGSHGPL
LPLPSRYRMG SRDTPELVAY PLPQASSSYM HGGNPSGSVV MVSGLHQLKM NCSRVFNLFC
LYGNIEKVKF MKTIPGTALV EMGDEYAVER AVTHLNNVKL FGKRLNVCVS KQHSVVPSQI
FELEDGTSSY KDFAMSKNNR FTSAGQASKN IIQPPSCVLH YYNVPLCVTE ETFTKLCNDH
EVLTFIKYKV FDAKPSAKTL SGLLEWECKT DAVEALTALN HYQIRVPNGS NPYTLKLCFS
TSSHL
//
