ID   A0A3Q7UHN8_VULVU        Unreviewed;      1079 AA.
AC   A0A3Q7UHN8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Glutamate receptor-interacting protein 2 isoform X2 {ECO:0000313|RefSeq:XP_025872712.1};
GN   Name=GRIP2 {ECO:0000313|RefSeq:XP_025872712.1};
OS   Vulpes vulpes (Red fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes.
OX   NCBI_TaxID=9627 {ECO:0000313|Proteomes:UP000286640, ECO:0000313|RefSeq:XP_025872712.1};
RN   [1]
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (JAN-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_025872712.1}
RP   IDENTIFICATION.
RC   STRAIN=TameXAggressive cross {ECO:0000313|RefSeq:XP_025872712.1};
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_025872712.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_025872712.1; XM_026016927.1.
DR   AlphaFoldDB; A0A3Q7UHN8; -.
DR   STRING; 9627.ENSVVUP00000018733; -.
DR   Proteomes; UP000286640; Unplaced.
DR   CDD; cd00992; PDZ_signaling; 7.
DR   Gene3D; 2.30.42.10; -; 7.
DR   InterPro; IPR043545; GRIP1/2.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR041489; PDZ_6.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR46227:SF4; GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2; 1.
DR   PANTHER; PTHR46227; GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP; 1.
DR   Pfam; PF00595; PDZ; 6.
DR   Pfam; PF17820; PDZ_6; 1.
DR   SMART; SM00228; PDZ; 7.
DR   SUPFAM; SSF50156; PDZ domain-like; 8.
DR   PROSITE; PS50106; PDZ; 7.
PE   4: Predicted;
KW   Receptor {ECO:0000313|RefSeq:XP_025872712.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286640}.
FT   DOMAIN          48..167
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          184..270
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          284..368
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          492..567
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          593..677
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          692..774
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          978..1060
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          60..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          409..484
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          775..806
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          820..900
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        412..451
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        775..798
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1079 AA;  116616 MW;  7DC69495BB0D2D71 CRC64;
     MLCGLSRETP GEADDGPYSK GGKDAGGTDM ALACRRQSIP EEFRGVTMVE LNKKEGSTLG
     LTISGGTDKD GKPRVSNLRP GGLAASFPSV KWGLRDHKDS TEEWCECWHP SPCMCSGLLA
     PRSDLLNVGD YIRSVNGIHL TRLRHDEIIT LLKNVGERVV LEVEYELPPP APENNPGIIT
     KTVDVSLYKE GNSFGFVLRG GAHEDIHKTR PLVLTYVRPG GPADREGSLK VGDRLLSVDG
     IPLHGASHAT ALATLRQCSH EALFQVEYDV AIPDTVANAS GPLIVEITKT PGSALGISLS
     TGSHRNKPVI TIDRIKPASV VDRSGALHAG DHILSIDGTS TEHCSLLEAT KLLANVSETV
     RLEILPAPHS RRPLKPSEAV KVQRSEQPHR WDPCVLSCHS PRPGHCRTPT WATPAGQDQS
     RSLSSTPFSS PTMNHAFPCT NPSTLPRGSH PMSPRTTMGR RRQRRREHKS SLSLASSTVG
     PGGQIVHTET TEVVLCGDPL SGFGLQLQGG IFATETLSSP PLVRFIEPDS PAERCGLLQV
     GDRVLSINGI ATEDGTMEEA NQLLRDAALA HKVVLEVEFD VAESVIPSSG TFHVKLPKRR
     GVELGITIGS TSRKRGEPLI ISDIKKGSVA HRTGTLEPGD KLLAIDNIRL DNCPMEDAVQ
     ILRQCEDLVK LKIRKDEDNS DEQETTGAIS YTVELKRYGG PLGITISGTE EPFDPIVISG
     LTKRGLAERT GAIHVGDRIL AINSVSLKGR PLSEAIHLLQ VAGETVTLKI KKQLDRPLPR
     HKSGSLSEAS DADEDPPEAL KGGLLPARFS PAVPSVDSAV ESWDSSATEG GFGGPGSYTA
     QAAARGMTPQ EWRPSRLRSS PPPTEPRRMS YTPAPTDESF PEEEEEEDWE PPTSPAPGPA
     REEGFWRMFG EALEDLESCG QSELLRELEA SIMTGTVQSV ALEGRPSQRP WRRGQEVRGA
     SPEEIQELLL PTPLEMHKVT LHKDPLRNDF GFSVSDGLLE KGVYVHTVRP DGPAQRGGLR
     PFDRVLQVNH VRTRDFDCCL AVPLLAEAGD VLALVISRNP LAQSSRAPRA PGPSSPRML
//